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Clostridium difficile colitis - a role of surgery

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MITÁŠ Ladislav SKŘIČKA Tomáš KALA Zdeněk POLÁK Pavel PENKA Igor HANSLIÁNOVÁ Markéta HEMMELOVÁ Beáta

Rok publikování 2015
Druh Článek v odborném periodiku
Časopis / Zdroj Acta Medica Medianae
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.5633/amm.2015.0113
Obor Chirurgie včetně transplantologie
Klíčová slova Clostridium difficile colitis; toxic colitis; surgery
Popis Clostridium difficile infection (CDI) is the most frequent cause of nococomial diarrhoea. Most cases are succesfully treated by antibiotic therapy, but nearly 10% may progress to the fulminant form. The aim of this work is a retrospective evaluation of the results of surgical treatment of patients with the severe Costridium colitis, in the period 2008-2014. Clostridium toxins were detected in patients in Bohunice University Hospital in 1956. Thirty seven of them underwent surgery due to toxic colitis. There were 6 total colectomies with terminal ileostomy, 29 subtotal colectomies with terminal ileostomy, 1 coecostomy and 1 axial ileostomy. The 30-day mortality was nearly 35 %, 90- day mortality 54% and morbidity 89%. Early and precise indication for surgery could save about 65% of patients with fulminant course of Clostridium difficile colitis.

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