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Diode laser thermal vaporization inductively coupled plasma mass spectrometry

Basic information
Original title:Diode laser thermal vaporization inductively coupled plasma mass spectrometry
Authors:Pavla Foltynová, Viktor Kanický, Jan Preisler
Further information
Citation:FOLTYNOVÁ, Pavla, Viktor KANICKÝ a Jan PREISLER. Diode laser thermal vaporization inductively coupled plasma mass spectrometry. Analytical Chemistry, Washington, D.C., USA: American Chemical Society, 2012, roč. 84, č. 5, s. 2268–2274. ISSN 0003-2700. doi:10.1021/ac202884m.Export BibTeX
@article{975037,
author = {Foltynová, Pavla and Kanický, Viktor and Preisler, Jan},
article_location = {Washington, D.C., USA},
article_number = {5},
doi = {http://dx.doi.org/10.1021/ac202884m},
keywords = {Laser ablation; inductively coupled plasma; mass spectrometry; sample introduction; diode laser; pyrolysis; thermal vaporization},
language = {eng},
issn = {0003-2700},
journal = {Analytical Chemistry},
title = {Diode laser thermal vaporization inductively coupled plasma mass spectrometry},
url = {http://pubs.acs.org/journals/ancham/index.html},
volume = {84},
year = {2012}
}
Original language:English
Field:Analytic chemistry
WWW:link to a new windowhttp://pubs.acs.org/journals/ancham/index.html
Type:Article in Periodical
Keywords:Laser ablation; inductively coupled plasma; mass spectrometry; sample introduction; diode laser; pyrolysis; thermal vaporization

An approach of sample introduction for inductively coupled mass spectrometry (ICPMS), diode laser thermal vaporization (DLTV) is described. The method allows quantitative determination of metals in submicroliter volumes of liquid samples. Laser power is sufficient to induce pyrolysis of a suitable substrate with the deposited sample leading to aerosol generation. Unlike existing sample introduction systems based on laser ablation, it uses a NIR diode laser rather than an expensive high-energy pulsed laser. For certain elements, this sample introduction technique may serve as an alternative to solution analysis with conventional nebulizers. Using a prearranged calibration set, DLTV ICPMS provides rapid and reproducible sample analysis (RSD 10%). Sample preparation is fast and simple, and the prepared samples can easily be archived and transported. The limits of detection for Co, Ni, Zn, Mo, Cd, Sn, and Pb deposited on the preprinted paper were found to be in the range of 0.4–30 pg. The method was characterized, optimized, and applied to the determination of Co in a drug preparation, Pb in whole blood, and Sn in food samples without any sample pretreatment.

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