Publication details


MicroRNAs and Glioblastoma

Basic information
Original title:MicroRNAs and Glioblastoma
Authors:Jiří Šána, Radek Lakomý, Marian Hajdúch, Ondřej Slabý
Further information
Citation:ŠÁNA, Jiří, Radek LAKOMÝ, Marian HAJDÚCH a Ondřej SLABÝ. MicroRNAs and Glioblastoma. In Ondrej Slaby. MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets. New York: Nova Science Publishers, Inc., 2012. s. 169-176, 8 s. Neuveden. ISBN 978-1-61324-514-9.Export BibTeX
author = {Šána, Jiří and Lakomý, Radek and Hajdúch, Marian and Slabý, Ondřej},
address = {New York},
booktitle = {MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets},
editor = {Ondrej Slaby},
keywords = {microRNAs; glioblastoma},
howpublished = {tištěná verze "print"},
language = {eng},
location = {New York},
isbn = {978-1-61324-514-9},
pages = {169-176},
publisher = {Nova Science Publishers, Inc.},
title = {MicroRNAs and Glioblastoma},
year = {2012}
Original language:English
Field:Oncology and hematology
Type:Chapter of a book
Keywords:microRNAs; glioblastoma

Glioblastoma is the highly malignant brain tumor with very poor prognosis. Despite great progress, current therapeutic approaches are insufficient for total cure of patients afflicted with this malignity. MiRNAs represent promising therapeutic targets in glioblastoma. In this chapter we summarize the current knowledge about miRNAs significance in glioblastoma, with special focus on their involvement in core signaling pathways, their roles in drug resistance and potential clinical implications.