A telomerase-independent component of telomere loss in chromatin assembly factor 1 mutants of Arabidopsis thaliana

• Authors: JAŠKE Karin; MOKROŠ Petr; MOZGOVÁ Iva; FOJTOVÁ Miloslava; FAJKUS Jiří
• Year of publication: 2013
• Type: Article in Periodical
• Magazine / Source: Chromosoma
• MU Faculty or unit: Central European Institute of Technology
• Doi: http://dx.doi.org/10.1007/s00412-013-0400-6
• Field: Genetics and molecular biology
• Keywords: Telomere; Chromatin assembly; Replication; Chromosome instability
• Description: Dysfunction of chromatin assembly factor 1 in FASCIATA mutants (fas) of Arabidopsis thaliana results in progressive loss of telomeric DNA. We conclude that in addition to possible impairment of telomerase action, a further mechanism contributes to telomere shortening in fas mutants.

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