Publication details

Intellectual Performance of Children of Mothers with an Untreated Thyroid Disorder in the First Pregnancy Trimester

Authors

KOMENDOVÁ Irena ŠPITÁLNÍKOVÁ Sylvie

Year of publication 2018
Type Article in Periodical
Magazine / Source Endokrynologia Polska
MU Faculty or unit

Faculty of Arts

Citation
Web http://dx.doi.org/10.5603/EP.a2018.0025
Doi http://dx.doi.org/10.5603/EP.a2018.0025
Keywords Attention-Deficit Disorders (ADD); Intelligence; Specific Learning Disorders (SLD); pregnancy; thyreoperoxidase antibodies; thyrotropin
Attached files
Description Abstract Introduction: The focus of the present study was the importance of the mother’s thyroid function for foetal development in the first trimester, when the baby is totally dependent on the mother for thyroid hormones. Materials and methods: The study consisted of testing the intellectual performance of children with both euthyroid and thyroid-dysfunction mothers. The experimental group comprised 60 children of mothers with an untreated thyroid disorder in the first trimester of pregnancy (TSH >/= 3.5 mlU/L [standard 0.15–3.5] and/or TPO-Ab >/= 20 lU/L [standard < 20]). The control group contained 132 children whose mothers showed no symptoms of a thyroid disorder either before or during pregnancy/postpartum. Both groups of children were administered the Wechsler Intelligence Scale for Children — Third Edition (WISC-III), whereby the intellectual performance of the experimental-group children was compared with that of the control-group children. The comparison included the percentage of children with IQ

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