Publication details

Neglected aspects of tick-borne rickettsioses

Authors

TOMASSONE Laura PORTILLO Aranzazu NOVÁKOVÁ Markéta SOUSA Rita de OTEO Jose Antonio

Year of publication 2018
Type Article in Periodical
Magazine / Source PARASITES & VECTORS
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1186/s13071-018-2856-y
Keywords Rickettsia spp.; Ticks; Vertebrate hosts; Candidatus; Epidemiology
Description Rickettsioses are among the oldest known infectious diseases. In spite of this, and of the extensive research carried out, many aspects of the biology and epidemiology of tick-borne rickettsiae are far from being completely understood. Their association with arthropod vectors, the importance of vertebrates as reservoirs, the rarity of clinical signs in animals, or the interactions of pathogenic species with rickettsial endosymbionts and with the host intracellular environment, are only some examples. Moreover, new rickettsiae are continuously being discovered. In this review, we focus on the 'neglected' aspects of tick-borne rickettsioses and on the gaps in knowledge, which could help to explain why these infections are still emerging and re-emerging threats worldwide.

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