Publication details

Epidemiology of plasma cell leukemia in the Czech Republic

Authors

ZAPLETALOVÁ Michaela KREJČÍ Denisa JARKOVSKÝ Jiří MUŽÍK Jan DUŠEK Ladislav POUR Luděk

Year of publication 2019
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.linkos.cz/casopis-klinicka-onkologie/2019-02-15-1/epidemiologie-plazmocelularni-leukemie-v-ceske-republice/
Doi http://dx.doi.org/10.14735/amko201947
Keywords plasma cell leukemia; epidemiology; Czech National Cncer Registry; Czech Republic
Attached files
Description BACKGROUND: Plasma cell leukemia (PCL) is a rare but most aggressive form of monoclonal gammopathies. PCL is characterized by the presence of clonal plasma cells in peripheral blood. There are two forms of PCL - primary which presents de novo in patients with no evidence of previous multiple myeloma and secondary which is a leukemic transformation of relapsed or refractory disease in patients with previously recognized multiple myeloma. Data from registries such as the CNCR can provide useful information on epidemiology of various dis-eases. These data, however, have several limitations, such as dia-gnostic criteria and proper coding of not only the dis-ease itself, but also its various forms. These limitations have to be taken into account during the process of results interpretation.

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