Limited efficacy of daratumumab in multiple myeloma with extramedullary disease

• Authors: JELINEK Tomas; SEVCIKOVA Tereza; ZIHALA David; POPKOVA Tereza; KAPUSTOVA Veronika; BROSKEVICOVA Lucie; CAPKOVA Lenka; ŘÍHOVÁ Lucie; BEZDĚKOVÁ Renata; ŠEVČÍKOVÁ Sabina; ZIDLIK Vladimir; HAVEL Martin; PLONKOVA Hana; JUNGOVA Alexandra; MINARIK Jiri; ŠTORK Martin; POUR Luděk; PAVLICEK Petr; SPICKA Ivan; MAISNAR Vladimir; RADOCHA Jakub; SIMICEK Michal; HAJEK Roman
• Year of publication: 2022
• Type: Article in Periodical
• Magazine / Source: Leukemia
• MU Faculty or unit: Faculty of Medicine
• Web: https://www.nature.com/articles/s41375-021-01343-w
• Doi: http://dx.doi.org/10.1038/s41375-021-01343-w
• Keywords: daratumumab; multiple myeloma; extramedullary disease; efficacy
• Description: The treatment of multiple myeloma (MM) has changed substantially during the past two decades. The incorporation of novel agents into therapeutic strategies has resulted in prolonged overall survival of MM patients with approximately 15% of them being considered operationally cured.

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