Capillary Microreaction Method Development for Drug Discovery Support

• Authors: ZEISBERGEROVÁ Marta; KONEČNÝ Jiří; GLATZ Zdeněk; HOOGMARTENS Jos; VAN SCHEPDAEL Ann
• Year of publication: 2008
• Type: Article in Proceedings
• Conference: Book of Abstracts 22nd International Symposium on MicroScale Bioseparations and Methods for Systems Biology
• MU Faculty or unit: Faculty of Science
• Field: Biochemistry
• Keywords: drug metabolism; microsomes; cytochrome P450; EMMA; microreaction
• Description: The presented EMMA method could be integrated in preliminary studies at first stage of drug discovery. This method could help to screen new drug candidates. There is no need for radiolabeling, minimal sample preparation and consumption and thus it can speed up data throughput and decrease the operational costs.

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