Publication details

Sister chromatids caught in the cohesin trap

Authors

ŠPÍREK Mário CIPAK Lubos GREGAN Juraj

Year of publication 2006
Type Article in Periodical
Magazine / Source NATURE STRUCTURAL & MOLECULAR BIOLOGY
MU Faculty or unit

Faculty of Science

Citation
Web http://www.nature.com/nsmb/journal/v15/n9/abs/nsmb0908-899.html
Field Biochemistry
Keywords cohesin; chromatid
Description Cohesin is a large ring-shaped protein complex that mediates cohesion between sister chromatids. New experiments show that the sister chromatids of a minichromosome are entrapped by monomeric cohesin rings, thus excluding the possibility that sister chromatid cohesion is mediated by nontopological interactions between cohesin complexes.

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