Publication details
Sister chromatids caught in the cohesin trap
Authors | |
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Year of publication | 2006 |
Type | Article in Periodical |
Magazine / Source | NATURE STRUCTURAL & MOLECULAR BIOLOGY |
MU Faculty or unit | |
Citation | |
Web | http://www.nature.com/nsmb/journal/v15/n9/abs/nsmb0908-899.html |
Field | Biochemistry |
Keywords | cohesin; chromatid |
Description | Cohesin is a large ring-shaped protein complex that mediates cohesion between sister chromatids. New experiments show that the sister chromatids of a minichromosome are entrapped by monomeric cohesin rings, thus excluding the possibility that sister chromatid cohesion is mediated by nontopological interactions between cohesin complexes. |