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Imunologické principy bezpečného očkování dětí

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Title in English Immunological principles of safety vaccination in children
Authors

THON Vojtěch

Year of publication 2010
Type Article in Periodical
Magazine / Source Pediatrie pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Immunology
Keywords vaccination; BCG; BCG-osis; hexavalent vaccine; rotavirus; TREC; immunodeficiency
Description The requirement of successful vaccination is safety. In past iatrogenic injuries of children after vaccination, incl. deaths were documented in the Czech Republic because of vaccine interactions and insufficient respect to contraindications. Therefore we recommend changing of current practice of BCG vaccination considering new immunization schedule with hexavalent vaccine. We advise to postpone BCG vaccination until the second half of the first year of life which is in accordance with the WHO and leads even to the protection of avian mycobacteriosis. Moreover, implementation of TRECs into the newborn screening from dried blood spot would increase the preventive approach to early immunodeficiency diagnostics.
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