Publication details
Epigenetická toxicita komplexních vzorků cyanobakterií - vliv ozonace a chlorace.
| Title in English | Epigenetic toxicity of cyanobacterial extracts: eff ects of ozonation and chlorination |
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| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Bulletin VÚRH Vodňany |
| MU Faculty or unit | |
| Citation | |
| Field | Environment influence on health |
| Keywords | cyanobacterial extract; cyanotoxins; inhibition of gap junctional intercellular communication; epigenetic toxicity; ozonation; chlorination |
| Description | A known tumor promoter, microcystin-LR, was detected in the extract by HPLC-DAD, but this cyanotoxin has been shown not to affect GJIC/MAPK in this in vitro model, thus the effects observed in our study were most likely caused by not-yet-identified chemicals of cyanobacterial origin. Although chemical identity of the responsible agents remains to be elucidated, the information on rapid elimination of the tumor promoting activity and cytotoxicity of cyanobacteria by ozone might have a particular importance for selection of the best technology for drinking water treatment from cyanobacteria-contaminated reservoirs. |
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