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Does repetitive transcranial magnetic stimulation have a positive effect on working memory and neuronal activation in treatment of negative symptoms of schizophrenia?

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Original title:Does repetitive transcranial magnetic stimulation have a positive effect on working memory and neuronal activation in treatment of negative symptoms of schizophrenia?
Authors:Radovan Přikryl, Michal Mikl, Hana Přikrylová Kučerová, Libor Ustohal, Tomáš Kašpárek, Radek Mareček, Michaela Vrzalová, Eva Češková, Jiří Vaníček
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Original language:English
Field:Psychiatry, sexuology
WWW:link to a new windowhttp://www.ncbi.nlm.nih.gov/pubmed/22467118
Type:Article in Periodical
Keywords:cognitive functions; fMRI; neuronal activation; negative symptoms;
Attached files:link to a new windowNEL rTMS negSCH fMRI 2012.pdf

Stimulation treatment led to a reduction of seriousness of negative schizophrenia symptoms in both comparative groups. However, mutual comparison of real (n=19) and sham (n=11) rTMS, respectively, has shown that the effect of real rTMS was statistically significantly higher compared with placebo stimulation. During stimulation treatment an improvement in working memory performance was also found. No statistically significant difference between the real and placebo sham rTMS, respectively, was established. The rate of neuronal activation did not change at all during rTMS treatment.

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