Publication details
MicroRNAs and Breast Cancer
| Basic information | |
|---|---|
| Original title: | MicroRNAs and Breast Cancer |
| Authors: | Martina Rédová, Marek Svoboda, Rostislav Vyzula |
| Further information | |
|---|---|
| Citation: | RÉDOVÁ, Martina, Marek SVOBODA and Rostislav VYZULA. MicroRNAs
and Breast Cancer. In Ondrej Slaby. MicroRNAs in Solid Cancer:
From Biomarkers to Therapeutic Targets. New York: Nova Science
Publishers, Inc., 2012. p. 81 -94, 14 pp. Neuveden. ISBN
978-1-61324-514-9.Export BibTeX@inbook{984810, author = {Rédová, Martina and Svoboda, Marek and Vyzula, Rostislav}, address = {New York}, booktitle = {MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets}, editor = {Ondrej Slaby}, keywords = {microRNAs; breast cancer}, howpublished = {tištěná verze "print"}, language = {eng}, location = {New York}, isbn = {978 -1-61324-514-9},pages = {81 -94},publisher = {Nova Science Publishers, Inc.}, title = {MicroRNAs and Breast Cancer}, year = {2012} } |
| Original language: | English |
| Field: | Oncology and hematology |
| Type: | Chapter of a book |
| Keywords: | microRNAs; breast cancer |
Breast cancer is a heterogeneous disease, comprising multiple entities associated with distinctive histological and biological features, clinical presentations and behaviours and responses to therapy. It is the second leading cause of cancer death in women. Despite improvement in treatment over the past few decades, there is an urgent need for development of targeted therapies. MicroRNAs (miRNAs) regulate diverse cellular processes and play an integral role in cancer pathogenesis. Emerging evidences suggest the involvement of altered regulation of miRNAs in the pathogenesis of breast cancer. MiRNAs are therefore thought to be functional as tumor suppressors or oncogenes, and as a consequence not only potential effective biomarkers, but also novel class of therapeutic targets.
