Informace o publikaci

Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.

Název česky Kryokonzervace spermatu před léčbou karcinomu varlat a jeho následné použití v léčbě infertlity
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ŽÁKOVÁ Jana LOUSOVÁ Eva VENTRUBA Pavel CRHA Igor POCHOPOVÁ Hana TESAŘOVÁ Eva VINKLÁRKOVÁ Jaroslava NUSSIR Mohamed Ismail Abdo

Rok publikování 2014
Druh Článek v odborném periodiku
Časopis / Zdroj The Scientific World Journal
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1155/2014/575978
Obor Gynekologie a porodnictví
Klíčová slova sperm cryopreservation testicular cancer infertility treatment
Popis Aims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm. Results. A total of 557 men have decided to freeze their semen before cancer treatment. Azoospermia was diagnosed in 34 men (6.1%), and semen was cryopreserved in 532 patients. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate. Conclusion. The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.

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