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Clinical impact of CYP2D6 activity in long-term paroxetine treatment

Basic information
Original title:Clinical impact of CYP2D6 activity in long-term paroxetine treatment
Authors:Alexandra Žourková, Eva Hadašová, Lucie Pulkrábková, Barbora Ravčuková, Tomáš Kašpárek
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Original language:English
Field:Psychiatry, sexuology
Type:Chapter of a book
Keywords:anxiety disorder - paroxetine - side effects - CYP2D6 - phenotype - genotype

The aim of study was comparison of distribution of therapeutic efficaccy and side effects of long-term paroxetine treatment according to metabolic status. Statistically significant difference was only in poor metabolisers CYP2D6 in severity of sexual dysfunction.

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