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Trombotická trombocytopenická purpura (TTP) u pacientky s roztroušenou sklerózou - kasuistika

Basic information
Original title:Trombotická trombocytopenická purpura (TTP) u pacientky s roztroušenou sklerózou - kasuistika
Authors:Petra Praksová, Pavel Štourač, Josef Bednařík
Further information
Citation:PRAKSOVÁ, Petra, Pavel ŠTOURAČ a Josef BEDNAŘÍK. Trombotická trombocytopenická purpura (TTP) u pacientky s roztroušenou sklerózou - kasuistika. Česká a slovenská neurologie a neurochirurgie, Praha: Česká lékařská společnost J.E.Purkyně, 2009, roč. 72/105, č. 1, s. 69-71. ISSN 1210-7859.Export BibTeX
@article{866675,
author = {Praksová, Petra and Štourač, Pavel and Bednařík, Josef},
article_location = {Praha},
article_number = {1},
keywords = {sclerosis multiplex; thrombocytopenia; microangiopathic hemolytic anemia; metaloproteinasis ADAMTS13; thrombotic thrombocytopenic purpura},
language = {eng},
issn = {1210-7859},
journal = {Česká a slovenská neurologie a neurochirurgie},
title = {Trombotická trombocytopenická purpura (TTP) u pacientky s roztroušenou sklerózou - kasuistika},
volume = {72/105},
year = {2009}
}
Original language:English
Field:Neurology, neurosurgery, neurosciences
Type:Article in Periodical
Keywords:sclerosis multiplex; thrombocytopenia; microangiopathic hemolytic anemia; metaloproteinasis ADAMTS13; thrombotic thrombocytopenic purpura

The authors report a case of 37-year old woman with multiple sclerosis who developed severe thrombocytopenia, anemia, renal insufficiency and neurological symptoms. The disease was classified as an attack of thrombotic thrombocytopenic purpura (TTP), Interferon beta and azathioprine therapy was discontinued due to possible association with the development of TTP. The patient was treated with corticosteroids, with a good therapeutic result. After 10 months, the attack of thrombotic thrombocytopenic purpura recurred. The article describes the principal clinical symptoms of this rare, but serious disorder.