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Trombotická trombocytopenická purpura (TTP) u pacientky s roztroušenou sklerózou - kasuistika

Základní údaje
Originální název:Trombotická trombocytopenická purpura (TTP) u pacientky s roztroušenou sklerózou - kasuistika
Autoři:Petra Praksová, Pavel Štourač, Josef Bednařík
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Originální jazyk:angličtina
Obor:Neurologie, neurochirurgie, neurovědy
Druh:Článek v odborném periodiku
Klíčová slova:sclerosis multiplex; thrombocytopenia; microangiopathic hemolytic anemia; metaloproteinasis ADAMTS13; thrombotic thrombocytopenic purpura

The authors report a case of 37-year old woman with multiple sclerosis who developed severe thrombocytopenia, anemia, renal insufficiency and neurological symptoms. The disease was classified as an attack of thrombotic thrombocytopenic purpura (TTP), Interferon beta and azathioprine therapy was discontinued due to possible association with the development of TTP. The patient was treated with corticosteroids, with a good therapeutic result. After 10 months, the attack of thrombotic thrombocytopenic purpura recurred. The article describes the principal clinical symptoms of this rare, but serious disorder.