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Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma

Basic information
Original title:Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma
Authors:Martina Rédová, Alexandr Poprach, Jana Nekvindová, Robert Iliev, Lenka Radová, Radek Lakomý, Marek Svoboda, Rostislav Vyzula, Ondřej Slabý
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Original language:English
Field:Oncology and hematology
WWW:link to a new windowhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340316/?tool=pubmed
Type:Article in Periodical
Keywords:Renal cell carcinoma; MicroRNA; Serum; Biomarker

There is no standard serum biomarker used for diagnosis or early detection of recurrence for renal cell carcinoma (RCC) patients. MicroRNAs (miRNAs) are abundant and highly stable in blood serum, and have been recently described as powerful circulating biomarkers in a wide range of solid cancers. Our aim was to identify miRNA signature that can distinguish the blood serum of RCC patients and matched healthy controls and validate identified miRNAs as potential biomarkers for RCC.

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