Research Project Results

 

Mapování výskytu makrolidové rezistence původce syfilis v ČR a molekulární typizace jednotlivých syfilitických kmenů

Project Identification:NT11159
MU Investigator:Assoc. Prof. MUDr. David Šmajs, Ph.D.
MU Faculty/Unit:Faculty of Medicine
Project Period:9/2010 - 12/2014
Investor/Programme:Ministry of Health of the CR / Ministry of Health's Departmental Research and Development Programme III (2010-2015)-
Cooperating Organization:
link to a new windowNational Institute of Public Health Prague 10 - Vinohrady

Publications:

2013

ČEJKOVÁ, Darina - ZOBANÍKOVÁ, Marie - POSPÍŠILOVÁ, Petra - STROUHAL, Michal - MIKALOVÁ, Lenka - WEINSTOCK, G.M. - ŠMAJS, David.
Structure of rrn operons in pathogenic non-cultivable treponemes: sequence but not genomic position of intergenic spacers correlates with classification of Treponema pallidum and T. paraluiscuniculi strains. JOURNAL OF MEDICAL MICROBIOLOGY, BERKS, ENGLAND, SOC GENERAL MICROBIOLOGY, USA. ISSN 0022-2615, 2013, vol. 62, no. 2, pp. 196-207.

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2012

ŠMAJS, David - NORRIS, Steven J. - WEINSTOCK, George M.
Genetic diversity in Treponema pallidum: Implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws. Infection, Genetics and Evolution, AMSTERDAM, ELSEVIER SCIENCE BV, The Nederlands. ISSN 1567-1348, 2012, vol. 12, no. 2, pp. 191-202.

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FLASAROVÁ, Magdalena - POSPÍŠILOVÁ, Petra - MIKALOVÁ, Lenka - VALIŠOVÁ, Zuzana - DASTYCHOVÁ, Eliška - STRNADEL, Radim - KUKLOVÁ, Ivana - WOZNICOVÁ, Vladana - ZÁKOUCKÁ, Hana - ŠMAJS, David.
Sequencing-based Molecular Typing of Treponema pallidum Strains in the Czech Republic: All Identified Genotypes are Related to the Sequence of the SS14 Strain. Acta Dermato-Venereologica, , , USA. ISSN 0001-5555, 2012, vol. 92, no. 6, 669–674-6 pp.

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PĚTROŠOVÁ, Helena - ZOBANÍKOVÁ, Marie - ČEJKOVÁ, Darina - MIKALOVÁ, Lenka - POSPÍŠILOVÁ, Petra - STROUHAL, Michal - CHEN, Lei - QIN, Xiang - MUZNY, Donna M. - WEINSTOCK, George M. - ŠMAJS, David.
Whole Genome Sequence of Treponema pallidum ssp. pallidum, Strain Mexico A, Suggests Recombination between Yaws and Syphilis Strains. PLOS Neglected Tropical Diseases, , , USA. ISSN 1935-2735, 2012, vol. 6, no. 9, "nestrankovano"-10 pp. Art. No. e1832.

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2011

ŠMAJS, David - ŠTAUDOVÁ, Barbora - MICENKOVÁ, Lenka - ŠMARDA, Jan - VRBA, Martin - ŠEVČÍKOVÁ, Alena - VALIŠOVÁ, Zuzana - WOZNICOVÁ, Vladana.
Bacteriocin genes among E. coli strains: the incidence depends on genotype and phenotype of E. coli strains. 2011.

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MIKALOVÁ, Lenka - POSPÍŠILOVÁ, Petra - FLASAROVÁ, Magdalena - VALIŠOVÁ, Zuzana - WOZNICOVÁ, Vladana - ZÁKOUCKÁ, H. - KUKLOVÁ, I. - ŠMAJS, David.
Molecular detection and typing of Treponema pallidum ssp. pallidum in clinical samples based on sequencing of TP0136, TP0548 and 23S rRNA genes. 2011.

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MIKALOVÁ, Lenka - POSPÍŠILOVÁ, Petra - FLASAROVÁ, Magdalena - VALIŠOVÁ, Zuzana - WOZNICOVÁ, Vladana - ZÁKOUCKÁ, Hana - KUKLOVÁ, L - ŠMAJS, David.
Molecular detection and typing of Treponema pallidum ssp. pallidum in clinical samples based on sequencing of TP0136, TP0548 and 23S rRNA genes. Acta Microbiol. Imm. H., , , Hungary. ISSN 1217-8950, 2011, vol. 58, pp. 187-188.

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MIKALOVÁ, Lenka - POSPÍŠILOVÁ, Petra - FLASAROVÁ, Magdalena - ZÁKOUCKÁ, H - WOZNICOVÁ, Vladana - ŠMAJS, David.
Molecular detection of Treponema pallidum ssp. pallidum in clinical samples: sequencing of TP0136, TP0548 and 23S rRNA genes. 2011.

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MIKALOVÁ, Lenka - POSPÍŠILOVÁ, Petra - FLASAROVÁ, Magdalena - ŠMAJS, David.
Molekulární detekce, kmenová typizace a stanovení makrolidové rezistence původce syfilis – Treponema pallidum subsp. pallidum v klinickém materiálu. 2011.

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ŠMAJS, David - MIKALOVÁ, Lenka - ČEJKOVÁ, Darina - STROUHAL, Michal - ZOBANÍKOVÁ, Marie - POSPÍŠILOVÁ, Petra - NORRIS, Steven J. - WEINSTOCK, George M.
Whole Genome Analyses of Treponemes: New Targets for Strain- and Subspecies- Specific Molecular Diagnostics. In Syphilis - Recognition, Description and Diagnosis. Rijeka (Croatia) : InTech, 2011. Infectious Diseases, ISBN 978-953-307-554-9, pp. 19-34.

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