Prof. RNDr. Alois Kozubík, CSc.

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found: 139 records, displayed 1 - 100
 
2013

FEDR, Radek - PERNICOVÁ, Zuzana - SLABÁKOVÁ, Eva - STRAKOVÁ, Nicol - BOUCHAL, Jan - GREPL, Michal - KOZUBÍK, Alois - SOUČEK, Karel.
Automatic cell cloning assay for determining the clonogenic capacity of cancer and cancer stem-like cells. Cytometry Part A, John Wiley & Sons, Inc. ISSN 1552-4930, 2013.


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KAUCKÁ, Markéta - PLEVOVÁ, Karla - PAVLOVÁ, Šárka - JANOVSKÁ, Pavlína - SHAIK, Archana - VERNER, Jan - PROCHÁZKOVÁ, Jiřina - KREJČÍ, Pavel - KOTAŠKOVÁ, Jana - OVESNÁ, Petra - TICHÝ, Boris - BRYCHTOVÁ, Yvona - DOUBEK, Michael - KOZUBÍK, Alois - MAYER, Jiří - POSPÍŠILOVÁ, Šárka - BRYJA, Vítězslav.
The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte Migration. Cancer Research, USA, American Association for Cancer Research, USA. ISSN 0008-5472, 2013, vol. 73, no. 5, pp. 1491-1501.


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2012

KOČÍ, Lenka - CHLEBOVÁ, Kateřina - HÝŽĎALOVÁ, Martina - HOFMANOVÁ, Jiřina - JÍRA, Miroslav - KYSELA, Petr - KOZUBÍK, Alois - KALA, Zdeněk - KREJČÍ, Pavel.
Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo. Oncology letters, USA. ISSN 1792-1074, 2012, vol. 3, no. 4, pp. 913-916.


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VAŇHARA, Petr - HAMPL, Aleš - KOZUBÍK, Alois - SOUČEK, Karel.
Growth/differentiation factor-15: prostate cancer suppressor or promoter?. Prostate Cancer And Prostatic Diseases, United Kingdom, Nature Publishing Group, Great Britain. ISSN 1365-7852, 2012, vol. 15, no. 4, pp. 320-328.


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KREJČÍ, Pavel - AKLIAN, Anie - KAUCKÁ, Markéta - ŠEVČÍKOVÁ, Eva - PROCHÁZKOVÁ, Jiřina - MIKOLKA, Pavol - BÁLEK, Lukáš - POSPÍŠILOVÁ, Tereza - SPOUSTOVÁ, Tereza - BRYJA, Vítězslav - VESELÁ, Iva - KOZUBÍK, Alois - WEIS, MaryAnn - PAZNEKAS, W.A. - WOLF, J.H. - GUTKIND, J.S. - WILCOX, W.A. - WNAG JABS, E. - SALAZAR, Lisa - MAŠEK, Jan Kukla.
Receptor tyrosine kinases activate canonical WNT/beta catenin signaling via MAP kinase/LRP6 pathway and direct beta-Catenin phosphorylation. Plos One, USA. ISSN 1932-6203, 2012, vol. 7, no. 4, pp. 1-14.


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STARŠÍCHOVÁ, Andrea - HRUBÁ, Eva - SLABÁKOVÁ, Eva - PERNICOVÁ, Zuzana - PROCHÁZKOVÁ, Jiřina - PĚNČÍKOVÁ, Kateřina - ŠEDA, Václav - KABÁTKOVÁ, Markéta - VONDRÁČEK, Jan - KOZUBÍK, Alois - MACHALA, Miroslav - SOUČEK, Karel.
TGF-beta 1 signaling plays a dominant role in the crosstalk between TGF-beta 1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells. Cellular Signalling, NEW YORK, ELSEVIER SCIENCE INC, USA. ISSN 0898-6568, 2012, vol. 24, no. 8, pp. 1665-1676.


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BRYJA, Vítězslav - KREJČÍ, Pavel - KAUCKÁ, Markéta - POSPÍŠILOVÁ, Šárka - MAYER, Jiří - KOZUBÍK, Alois - PLEVOVÁ, Karla - KOTAŠKOVÁ, Jana.
Způsob stanovení závažnosti a prognózy B-buněčné chronické lymfocytární leukémie. . Patent. Czech Republic. 2012. Number: 303555. Owner: Masarykova Univerzita, Brno, CZ. Accepted: 24.10.2012.


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2011

PERNICOVÁ, Zuzana - SLÁBÁKOVÁ, Eva - KHARAISHVILI, Gvantsa - BOUCHAL, Jan - KRÁL, Milan - KUNICKÁ, Zuzana - MACHALA, Miroslav - KOZUBÍK, Alois - SOUČEK, Karel.
Androgen Depletion Induces Senescence in Prostate Cancer Cells through Down-regulation of Skp2. Neoplasia, Neoplasia Press, USA. ISSN 1522-8002, 2011, vol. 13, no. 6, pp. 526-536.


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KOČÍ, Lenka - HÝŽĎALOVÁ, Martina - VACULOVÁ, Alena - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells. Cytokine. ISSN 1043-4666, 2011, no. 55, p. 34-39.


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SKENDER, Belma - VACULOVÁ, Alena - SLAVÍK, Josef - MACHALA, Miroslav - KOZUBÍK, Alois - HOFMANOVÁ, Jiřina.
Docosahexaenoic acid sensitizes colon cancer cells to apoptotic effect of TRAIL by modulation of lipid and apoptotic signalling pathways. 2011.


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ČERVENKA, Igor - WOLF, Joshua - MAŠEK, Jan - KREJČÍ, Pavel - WILCOX, William R - KOZUBÍK, Alois - SCHULTE, Gunnar - GUTKIND, J Silvio - BRYJA, Vítězslav.
Mitogen-Activated Protein Kinases Promote WNT/beta-Catenin Signaling via Phosphorylation of LRP6. January 2011, Washington, D.C., ASM, USA. ISSN 0270-7306, 2011, vol. 31, no. 1, pp. 179-189.


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ČERVENKA, Igor - WOLF, Joshua - MAŠEK, Jan - KREJČÍ, Pavel - WILCOX, William R. - KOZUBÍK, Alois - SCHULTE, Gunnar - GUTKIND, Silvio J. - BRYJA, Vítězslav.
Mitogen-Activated Protein Kinases Promote WNT/beta-Catenin Signaling via Phosphorylation of LRP6. Molecular and cellular biology, USA. ISSN 0270-7306, 2011, vol. 31, no. 1, pp. 179-189.


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KAUCKÁ, Markéta - KREJČÍ, Pavel - PLEVOVÁ, Karla - PAVLOVÁ, Šárka - PROCHÁZKOVÁ, Jiřina - JANOVSKÁ, Pavlína - VALNOHOVÁ, Jana - KOZUBÍK, Alois - POSPÍŠILOVÁ, Šárka - BRYJA, Vítězslav.
Post-translational modifications regulate signalling by Ror1. Acta Physiologica, Oxford, Blackwell Publishing, Great Britain. ISSN 1748-1708, 2011, vol. 203, no. 3, pp. 351-362.


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SLABÁKOVÁ, Eva - PERNICOVÁ, Zuzana - SLAVÍČKOVÁ, Eva - STARŠÍCHOVÁ, Andrea - KOZUBÍK, Alois - SOUČEK, Karel.
TGF-beta1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug. The Prostate. ISSN 0270-4137, 2011.


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PROCHÁZKOVÁ, Jiřina - KABÁTKOVÁ, Markéta - BRYJA, Vítězslav - UMANNOVÁ, Lenka - BERNATÍK, Ondřej - KOZUBÍK, Alois - MACHALA, Miroslav - VONDRÁČEK, Jan.
The interplay of the aryl hydrocarbon receptor and beta-catenin alters both AhR-dependent transcription and Wnt/beta catenin signaling in liver progenitors. Toxicological sciences, Great Britain. ISSN 1096-6080, 2011, vol. 122, no. 2, pp. 349-360.


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KAUCKÁ, Markéta - VERNER, Jan - PROCHÁZKOVÁ, Jiřina - PLEVOVÁ, Karla - STEHLÍKOVÁ, Olga - KREJČÍ, Pavel - KOZUBÍK, Alois - MAYER, Jiří - POSPÍŠILOVÁ, Šárka - BRYJA, Vítězslav.
Wnt/PCP pathway regulates B-cell migration in chronic lymphocytic leukemia. 2011.


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2010

FOLDYNOVÁ-TRANTÍRKOVÁ, S. - SEKYROVÁ, P. - TMEJOVÁ, Kateřina - BRUMOVSKÁ, E. - BERNATÍK, Ondřej - BLANKENFELDT, W. - KREJČÍ, Pavel - KOZUBÍK, Alois - DOLEZAL, T. - TRANTÍREK, Lukáš - BRYJA, Vítězslav.
Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration. Breast Cancer Research, London, Great Britain, Biomed Central Ltd., Great Britain. ISSN 1465-5411, 2010, vol. 2010, no. 12/3, pp. 30-31.


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KREJČÍ, Pavel - PROCHÁZKOVÁ, Jiřina - SMUTNÝ, Jiří - CHLEBOVÁ, Katarína - LIN, Patricia - AKLIAN, Anie - BRYJA, Vítězslav - KOZUBÍK, Alois - WILCOX, William R..
FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence. Bone, USA, Elsevier Science, USA. ISSN 8756-3282, 2010, vol. neuveden, no. 47, pp. 102-110.


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SOUČEK, Karel - SLABÁKOVÁ, Eva - OVESNÁ, Petra - MALENOVSKÁ, Alice - KOZUBÍK, Alois - HAMPL, Aleš.
Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma. Hum. Reprod., Oxford, Oxford University Press, Great Britain. ISSN 0268-1161, 2010, vol. 25, no. 12, pp. 2962-71.


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KREJČÍ, Pavel - MURAKAMI, Shunichi - PROCHÁZKOVÁ, Jiřina - TRANTÍREK, Lukáš - CHLEBOVÁ, Katarína - SMUTNÝ, Jiří - BRYJA, Vítězslav - KOZUBÍK, Alois.
Nf449 is a novel inhibitor of fibroblast growth factor receptor 3 (fgfr3) signaling active in chondrocytes and multiple myeloma cells. J. Biol. Chem., USA. ISSN 0021-9258, 2010, vol. neuveden, no. 285, pp. 20644-20653.


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STARŠÍCHOVÁ, Andrea - LINCOVÁ, Eva - PERNICOVÁ, Zuzana - KOZUBÍK, Alois - SOUČEK, Karel.
TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells. Cell Signal. ISSN 0898-6568, 2010.


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2009

STIXOVÁ, Lenka - PROCHÁZKOVÁ, Jiřina - SOUČEK, Karel - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
5 lipoxygenase inhibitors potentiate 1alpha,25 dihydroxyvitamin D3 induced monocytic differentiation by activating p38 MAPK pathway. Mol Cell Biochem, The Nederlands. ISSN 0300-8177, 2009, vol. 330, no. 1-2, 10 pp.


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HOFMANOVÁ, Jiřina - VACULOVÁ, Alena - HÝŽĎALOVÁ, Martina - KOČÍ, Lenka - SKENDER, Belma - KOZUBÍK, Alois.
Dietary fatty acids modulate the effects of TNF family apoptic inducers. 2009.


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JENDZELOVSKY, Rastislav - MIKES, Jaromir - KOVAL, Jan - SOUČEK, Karel - PROCHÁZKOVÁ, Jiřina - KELLO, Martin - SACKOVA, Veronika - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - FEDOROČKO, Peter.
Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Great Britain. ISSN 1474-905X, 2009, vol. 8, no. 12, 8 pp.


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STARŠÍCHOVÁ, Andrea - KUBALA, Lukáš - LINCOVÁ, Eva - PERNICOVÁ, Zuzana - KOZUBÍK, Alois - SOUČEK, Karel.
Dynamic Monitoring of Cellular Remodeling Induced by the Transforming Growth Factor-beta 1. BIOLOGICAL PROCEDURES ONLINE, NEW YORK, SPRINGER. ISSN 1480-9222, 2009, vol. 11, no. 1, pp. 316-324.


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KREJČÍ, Pavel - PROCHÁZKOVÁ, Jiřina - BRYJA, Vítězslav - JELÍNKOVÁ, Petra - PEJCHALOVÁ, Kateřina - KOZUBÍK, Alois - TOMPSON, Leslie Michels - WILCOX, William R..
Fibroblast growth factor inhibits interferon gama-STAT1 and interleukin 6-STAT3 signaling in chondrocytes. Cellular Signalling, Great Britain. ISSN 0898-6568, 2009, vol. 21, no. 1, pp. 151-160.


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SKENDER, Belma - VONDÁLOVÁ BLANÁŘOVÁ, Olga - JELÍNKOVÁ, Iva - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Flow cytometric analysis of TNF-related apoptosis inducing ligand (TRAIL) internalization. 2009.


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VAŇHARA, Petr - LINCOVÁ, Eva - KOZUBÍK, Alois - JURDIC, Pierre - SOUČEK, Karel - ŠMARDA, Jan.
Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation. Differentiation, ELSEVIER, USA. ISSN 0301-4681, 2009, vol. 78, no. 4, pp. 213-222.


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HOFMANOVÁ, Jiřina - STIXOVÁ, Lenka - HÝŽĎALOVÁ, Martina - KOČÍ, Lenka - SKENDER, Belma - VACULOVÁ, Alena - KOZUBÍK, Alois.
Mitochondrial pathway in apoptotic and differentiation response of human colon cells to dietary fatty acids and TNF family cytokines. 2009.


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SKENDER, Belma - HÝŽĎALOVÁ, Martina - VACULOVÁ, Alena - KOZUBÍK, Alois - HOFMANOVÁ, Jiřina.
Modulation of TNF-related apoptosis inducing ligand apoptosis in colon cancer cells by omega-3 docosahexaenoic fatty acid. 2009.


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KREJČÍ, Pavel - PROCHÁZKOVÁ, Jiřina - BRYJA, Vítězslav - KOZUBÍK, Alois - WILCOX, William.
Molecular pathology of the fibroblast growth factor family. Human Mutation, USA. ISSN 1059-7794, 2009, vol. 30, no. 9, pp. 1245-55.


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PROCHÁZKOVÁ, Jiřina - STIXOVÁ, Lenka - SOUČEK, Karel - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-alpha and MK886 requires activation of pro-apoptotic machinery. European Journal of Haematology, Denmark. ISSN 0902-4441, 2009, vol. 83, no. February, 13 pp.


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LINCOVÁ, Eva - HAMPL, Aleš - PERNICOVÁ, Zuzana - STARŠÍCHOVÁ, Andrea - KRČMÁŘ, Pavel - MACHALA, Miroslav - KOZUBÍK, Alois - SOUČEK, Karel.
Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs. Biochemical Pharmacology, Great Britain. ISSN 0006-2952, 2009, vol. 78, no. 6, pp. 561-572.


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LINCOVÁ, E - HAMPL, Aleš - PERNICOVÁ, Z - STARŠÍCHOVÁ, Andrea - KRČMÁŘ, P - MACHALA, M - KOZUBÍK, Alois - SOUČEK, Karel.
Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs. 2009.


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2008

KREJČÍ, Pavel - SALAZAR, Lisa - KASHIWADA, Tamara A. - CHLEBOVÁ, Katarína - SALAŠOVÁ, Alena - THOMPSON, Leslie Michels - BRYJA, Vítězslav - KOZUBÍK, Alois - WILCOX, William R..
Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage. PLoS ONE., USA. ISSN 1932-6203, 2008, vol. 3, no. 12, pp. 72-81.


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CHLEBOVÁ, Katarína - BRYJA, Vítězslav - DVOŘÁK, Petr - KOZUBÍK, Alois - WILCOX, W.R. - KREJČÍ, Pavel.
High molecular weight FGF2: the biology of a nuclear growth factor. Cellular and molecular life sciences : CMLS, Switzerland, Switzerland. ISSN 1420-682X, 2008, vol. 66, no. 2, pp. 225-235.


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SKENDER, Belma - HÝŽĎALOVÁ, Martina - VACULOVÁ, Alena - KOZUBÍK, Alois - HOFMANOVÁ, Jiřina.
Modulation of the effects of apoptotic inductors from the TNF family by dietary lipid components. 2008.


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UMANNOVÁ, Lenka - NEČA, Jiří - ANDRYSÍK, Zdeněk - VONDRÁČEK, Jan - UPHAM, BL - TROSKO, JE - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - MACHALA, Miroslav.
Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling. Toxicology, Amsterdam, Elsevier, The Nederlands. ISSN 0300-483X, 2008, vol. 247, no. 1, pp. 55-60.


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KOUBKOVÁ, Zuzana - HOFMANOVÁ, Jiřina - CIGÁNEK, Miroslav - SLAVÍK, Josef - SKENDER, Belma - MACHALA, Miroslav - KOZUBÍK, Alois.
Response of normal vs. cancer colon cells to short- and long-chain fatty acids. 2008.


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UMANNOVÁ, Lenka - MACHALA, Miroslav - TOPINKA, Jan - NOVÁKOVÁ, Zuzana - MILCOVÁ, Alena - KOZUBÍK, Alois - VONDRÁČEK, Jan.
Tumor necrosis factor-alpha potentiates genotoxic effects of benzo[a]pyrene in rat liver epithelial cells through upregulation of cytochrome P450 1B1 expression. MUTATION RESEARCH-Fundamental and Molecular Mechanisms of Mutagenesis, Elsevier. ISSN 0027-5107, 2008, vol. 640, no. 1-2, pp. 162-169.


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2007

PROCHÁZKA, L. - TURÁNEK, Jaroslav - TESAŘÍK, R. - KNOTIGOVÁ, P. - POLÁŠKOVÁ, P. - ANDRYSÍK, Zdeněk - KOZUBÍK, Alois - ŽÁK, F. - SOVA, P. - NEUŽIL, J. - MACHALA, M..
Apoptosis and inhibition of gap-junctional intecellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex. Archives of biochemistry and biophysics, New York, Academic Press, USA. ISSN 0003-9861, 2007, vol. 2007, no. 462, p. 54-61.


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VAŇHARA, Petr - BRYJA, Vítězslav - HORVÁTH, Viktor - KOZUBÍK, Alois - HAMPL, Aleš - ŠMARDA, Jan.
c-Jun induces apoptosis of serum-deprived BM2 monoblasts by activating cyclin A-associated CDK2 kinase. In Analytical Cytometry IV. Brno : Czech Society for Analytical Cytology, 2007. ISBN 978-80-239-9591-6, pp. 138-139. 23.6.2007, Brno.


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VAŇHARA, Petr - BRYJA, Vítězslav - HORVÁTH, Viktor - KOZUBÍK, Alois - HAMPL, Aleš - ŠMARDA, Jan.
c-Jun induces apoptosis of starved BM2 monoblasts by activating cyclin A-CDK2. Biochemical and Biophysical Research Communications, San Diego (USA), Academic Press, USA. ISSN 0006-291X, 2007, vol. 353, no. 1, pp. 92-97.


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VONDRÁČEK, Jan - ŠVIHÁLKOVÁ ŠINDLEROVÁ, Lenka - PĚNČÍKOVÁ, K. - MARVANOVÁ, S. - KRČMÁŘ, P. - CIGÁNEK, M. - NEČA, J. - TROSKO, J.E. - UPHAM, B. - KOZUBÍK, Alois - MACHALA, M..
Concentrations of methylated naphthalenes, anthracenes, and phenanthrenes occurring in czech river sediments and their effects on toxic events associated with carcinogenesis in rat liver cell lines. Environmental Toxicology and Chemistry, Pensacola, FL, USA, SETAC, USA. ISSN 0730-7268, 2007, vol. 2007, no. 26(11), p. 2308-2316.


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ŠVIHÁLKOVÁ ŠINDLEROVÁ, Lenka - MACHALA, Miroslav - PĚNČÍKOVÁ, K. - MARVANOVÁ, S. - NEČA, J. - TOPINKA, J. - SEVASTYANOVA, O. - KOZUBÍK, Alois - VONDRÁČEK, Jan.
Dibenzoanthracenes and benzochrysenes elicit both genotoxic and nongenotoxic events in rat liver stem-like cells. Toxicology, Amsterdam, Elsevier, The Nederlands. ISSN 0300-483X, 2007, vol. 2007, no. 232(1-2), p. 147-159.


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HORVÁTH, Viktor - SOUČEK, K. - ŠVIHÁLKOVÁ ŠINDLEROVÁ, Lenka - VONDRÁČEK, J. - BLANÁŘOVÁ, Olga - HOFMANOVÁ, Jiřina - SOVA, P. - KOZUBÍK, Alois.
Different cell cycle modulation following treatment of human ovarian carcinoma cells with a new platinum(IV) complex vs cisplatin. Investigational New Drugs, The Nederlands. ISSN 0167-6997, 2007, vol. 2007, no. 25(5), p. 435-443.


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HOFMANOVÁ, Jiřina - VACULOVÁ, Alena - HÝŽĎALOVÁ, Martina - KOZUBÍK, Alois.
Different response of normal and cancer human colon epithelial cells to dietary fatty acids and endogenous apoptotic regulators of TNF family. Nova Science Publishers, Inc., USA., 2007. Cell Apoptosis Research Trends.


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BÁRTOVÁ, Eva - PACHERNÍK, Jiří - KOZUBÍK, Alois - KOZUBEK, Stanislav.
Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites. Histochemistry and Cell Biology, Heidelberg, Springer, Germany. ISSN 0948-6143, 2007, vol. 2007, no. 127 (4), p. 375-388.


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SOLÁR, P. - HORVÁTH, Viktor - KLEBAN, J. - KOVAĽ, J. - SOLÁROVÁ, Z. - KOZUBÍK, Alois - FEDOROČKO, P..
Hsp90 inhibitor Geldanamycin increases the sensitivity of resistant ovarian adenocarcinoma cell line A2780cis to cisplatin. Neoplasma. ISSN 0028-2685, 2007, vol. 2007, no. 54, p. 127-130.


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SOUČEK, Karel - LINCOVÁ, Eva - STARŠÍCHOVÁ, Andrea - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Interaction between effects of vitamin D3 and nonsteroidal anti-inflammatory drugs in prostate and colon epithelial cells. In American Association for Cancer Research Annual Meeting Proceedings. Los Angeles, USA : American Association for Cancer Research, 2007. Abstract nr 3287-1 p. Los Angeles, USA.


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SOUČEK, Karel - LINCOVÁ, Eva - STARŠÍCHOVÁ, Andrea - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Interaction between effects of vitamin D3 and nonsteroidal anti-inflammatory drugs in prostate and colon epithelial cells. Brno : CSAC, 2007.


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NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - KOZUBÍK, Alois - ŠMARDA, Jan.
Lidský nádorový supresor p53 zastavuje růst a indukuje diferenciaci ptačích monoblastů. In Edukační sborník. Brno : Masarykoův onkologický ústav, 2007. ISBN 978-9780-86793-09-2, pp. 371-373. 23.4.2007, Brno.


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KLEBAN, J. - MIKEŠ, J. - SZILÁRDIOVÁ, B. - KOVAL, J. - SAČKOVÁ, V. - SOLÁR, P. - HORVÁTH, Viktor - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - FEDOROČKO, P..
Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells. Photochemistry and Photobiology, USA. ISSN 0031-8655, 2007, vol. 2007, no. 83, p. 1174-1185.


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MIKEŠ, J. - KLEBAN, J. - SAČKOVÁ, V. - HORVÁTH, Viktor - JAMBOROVÁ, E. - VACULOVÁ, Alena - KOZUBÍK, Alois - HOFMANOVÁ, Jiřina - FEDOROČKO, P..
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Great Britain. ISSN 1474-905X, 2007, vol. 2007, no. 6, p. 758 - 766.


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PACHERNÍK, Jiří - HORVÁTH, Viktor - KUBALA, Lukáš - DVOŘÁK, Petr - KOZUBÍK, Alois - HAMPL, Aleš.
Neural Differentiation Potentiated by the Leukaemia Inhibitory Factor through Stat3 Signalling in Mouse Embryonal Carcinoma Cells. Folia Biologica. ISSN 0015-5500, 2007, vol. 53, no. 5, pp. 157-163.


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ŠMARDA, Jan - NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - KOZUBÍK, Alois - LOJEK, Antonín.
p53 arrests growth and induces differentiation of v-myb-transformed monoblasts. In Molecular Aspects of myeloid stem cell development and leukemia. Annapolis, USA : Leukemia and Lymphoma Society, 2007. p. 64-64. 13.5.2007, Annapolis, USA.


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NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - KOZUBÍK, Alois - LOJEK, Antonín - LIPSICK, Joseph - ŠMARDA, Jan.
p53 arrests growth and induces differentiation of v-Myb-transformed monoblasts. Differentiation, Malden, USA, Blackwell Publishing, USA. ISSN 0301-4681, 2007, vol. 75, no. 7, pp. 592-604.


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NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - KOZUBÍK, Alois - LOJEK, Antonín - ŠMARDA, Jan.
Protein p53 zastavuje proliferaci a indukuje diferenciaci v-myb transformovaných monoblastů. In Chemické listy. Praha : Česká společnost chemická, 2007. ISBN 009-2770, p. 450-450. 12.6.2007, Devět skal - Žďárské vrchy.


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ANDRYSÍK, Zdeněk - VONDRÁČEK, Jan - MACHALA, Miroslav - KRČMÁŘ - ŠVIHÁLKOVÁ ŠINDLEROVÁ, Lenka - KRANZ, A. - WEISS, C. - FAUST, D. - KOZUBÍK, Alois - DIETRICH, C..
The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells. Mutation Research. ISSN 0165-1218, 2007, vol. 2007, no. 615, p. 87-97.


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UMANNOVÁ, Lenka - ZATLOUKALOVÁ, Jiřina - MACHALA, Miroslav - KRČMÁŘ, P. - MÁJKOVÁ, Z. - HENNINGS, B. - KOZUBÍK, Alois - VONDRÁČEK, Jan.
Tumor necrosis factor-α modulates effects of aryl hydrocarbon receptor ligands on cell proliferation and expression of cytochrome P450 enzymes in rat liver “stem-like“ cells. Toxicological sciences, Great Britain. ISSN 1096-6080, 2007, vol. 2007, no. 99 (1), p. 79-89.


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ZATLOUKALOVÁ, Jiřina - ŠVIHÁLKOVÁ ŠINDLEROVÁ, Lenka - KOZUBÍK, Alois - KRČMÁŘ, P. - MACHALA, Miroslav - VONDRÁČEK, Jan.
β-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells. Biochemical Pharmacology, Oxford, UK, Elsevier, Great Britain. ISSN 0006-2952, 2007, vol. 2007, no. 73(10), p. 1622-1634.


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2006

VONDRÁČEK, Jan - ŠVIHÁLKOVÁ ŠINDLEROVÁ, L. - PĚNČÍKOVÁ, K. - KRČMÁŘ, P - ANDRYSÍK, Z - CHRAMOSTOVÁ, K - MARVANOVÁ, S. - VALOVIČOVÁ, Ivana - KOZUBÍK, Alois - GÁBELOVÁ, A. - MACHALA, M..
7H-Dibenzoc,gcarbazole and 5,9-dimethyldibenzoc,gcarbazole exert multiple toxic events contributing to tumor promotion in rat liver epithelial stem-like, cells. Mutation Research. ISSN 0165-1218, 2006, vol. 2006, no. 596 (1-2), p. 43-56.


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ANDRYSÍK, Zdeněk - MACHALA, M. - CHRAMOSTOVÁ, K. - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - VONDRÁČEK, Jan.
Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis. Toxicology and applied pharmacology, USA. ISSN 0041-008X, 2006, vol. 2006, no. 211 (3), p. 198-208.


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VACULOVÁ, Alena - HOFMANOVÁ, Jiřina - SOUČEK, K. - KOZUBÍK, Alois.
Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAIL-sensitive and TRAIL-resistant colon cancer cells. FEBS Letters, Amsterdam, Elsevier, The Nederlands. ISSN 0014-5793, 2006, p. 6565-6569.


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VONDRÁČEK, Jan - SOUČEK, Karel - SHEARD, M.A. - CHRAMOSTOVÁ, K. - ANDRYSÍK, Z. - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization. Leukemia Research, The Nederlands. ISSN 0145-2126, 2006, vol. 2006, no. 30, p. 81-89.


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HOFER, Michal - POSPÍŠIL, M. - ZNOJIL, V, - HOLÁ, J. - VACEK, A. - WEITEROVÁ, Lenka - ŠTREITOVÁ, D. - KOZUBÍK, Alois.
Meloxicam, a cyclooxygenase 2 inhibitor, supports hematopoietic recovery in gamma-irradiated mice. Radiation Research, USA. ISSN 0033-7587, 2006, p. 556-560.


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ŠTIKA, Jiří - VONDRÁČEK, J. - HOFMANOVÁ, Jiřina - ŠIMEK, Vladimír - KOZUBÍK, Alois.
MK-886 enhances tumour necrosis factor--induced differentiation and apoptosis. Cancer Letters, OXFORD, ELSEVIER, Great Britain. ISSN 0304-3835, 2006, p. 263-271.


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NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - KOZUBÍK, Alois - LOJEK, Antonín - ŠMARDA, Jan.
p53 arrests growth and induces differentiation of v-Myb-transformed monoblasts. In ISREC conference on cancer research. Lausanne, Švýcarsko : Swiss Institute for Experimental Cancer Research, 2006. ISBN nepřiděleno, p. 77-77. 11.10.2006, Lausanne, Švýcarsko.


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NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - KOZUBÍK, Alois - LOJEK, Antonín - ŠMARDA, Jan.
p53 induces differentiation but not apoptosis of v-myb-transformed monoblasts. In International Journal of Molecular Medicine,. Greece : Lychnia, Athens, Greece, 2006. ISBN 1107-3756, p. S38-S38. 12.10.2006, Hersonissos, Crete, Greece.


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HORVÁTH, Viktor - BLANÁŘOVÁ, Olga - ŠVIHÁLKOVÁ ŠINDLEROVÁ, Lenka - SOUČEK, K. - HOFMANOVÁ, Jiřina - SOVA, P. - KROUTIL, A. - FEDOROČKO, P. - KOZUBÍK, Alois.
Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells. Gynecologic Oncology. ISSN 0090-8258, 2006, vol. 2006, no. 102(1), p. 32-40.


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KLEBAN, J. - SZILÁRDIOVÁ, B. - MIKEŠ, J. - HORVÁTH, Viktor - SAČKOVÁ, V. - BREZÁNI, P. - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - FEDOROČKO, P..
Pre-treatment of HT-29 cells with 5-LOX inhibitor (MK-886) induces changes in cell cycle and increases apoptosis after photodynamic therapy with hypericin. Journal of Photochemistry and Photobiology B: biology, Elsevier, The Nederlands. ISSN 1011-1344, 2006, p. 79-88.


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SOUČEK, Karel - PACHERNÍK, Jiří - KUBALA, Lukáš - VONDRÁČEK, Jan - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Transforming Growth Factor-Beta 1 Inhibits All-Trans Retinoic Acid-Induced Apoptosis. Leukemia Research. ISSN 0145-2126, 2006, vol. 30, no. 5, pp. 607-23.


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SOUČEK, Karel - PACHERNÍK, Jiří - KUBALA, Lukáš - VONDRÁČEK, Jan - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis. Leukemia Research. ISSN 0145-2126, 2006, vol. 30, no. 5, pp. 607-23.


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2005

VONDRÁČEK, J. - MACHALA, M. - BRYJA, V. - CHRAMOSTOVÁ, K. - KRČMÁR, P. - DIETRICH, C. - HAMPL, Aleš - KOZUBÍK, Alois.
Aryl Hydrocarbon Receptor-Activating Polychlorinated Biphenyls and Their Hydroxylated Metabolites Induce Cell Proliferation in Contact-Inhibited Rat Liver Epithelial Cells. Toxicological sciences, Great Britain. ISSN 1096-6080, 2005, vol. 83, no. 1, pp. 53-63.


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PLÍŠKOVÁ, M - VONDRÁČEK, Jan - VOJTĚŠEK, B - KOZUBÍK, Alois - MACHALA, M.
Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events. Toxicological sciences, Great Britain. ISSN 1096-6080, 2005.


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KOZUBÍK, Alois - HORVÁTH, V - ŠVIHÁLKOVÁ – ŠINDLEROVÁ, L - SOUČEK, K - HOFMANOVÁ, Jiřina - SOVA, P - KROUTIL, A - ŽÁK, F - MISTR, A - TURÁNEK, J.
High effectiveness of platinum (IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro. Biochemical Pharmacology, Oxford, UK, Elsevier, Great Britain. ISSN 0006-2952, 2005.


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HOFMANOVÁ, Jiřina - VACULOVÁ, Alena - LOJEK, Antonín - KOZUBÍK, Alois.
Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells. Europian Journal of Nutrition. ISSN 1436-6215, 2005, vol. 44, pp. 40-51.


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HOFMANOVÁ, Jiřina - VACULOVÁ, A. - LOJEK, Antonín - KOZUBÍK, Alois.
Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells. European Journal of Nutrition. ISSN 1436-6207, 2005, p. 40-51.


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HOFMANOVÁ, Jiřina - VACULOVÁ, Alena - KOZUBÍK, Alois.
Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis. Cancer Letters, OXFORD, ELSEVIER, Great Britain. ISSN 0304-3835, 2005, p. 33-41.


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HOFMANOVÁ, Jiřina - ZADÁK, Z - HYŠPLER, R - MIKESKA, J - ŽĎÁNSKÝ, P - VACULOVÁ, A - NETÍKOVÁ, J - KOZUBÍK, Alois.
The effects of parenteral lipid emulsions on cancer and normal human colon epithelial cells in vitro. Physiological Research, Praha, . ISSN 0862-8408, 2005.


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VACULOVÁ, A - HOFMANOVÁ, Jiřina - ANDĚRA, L - KOZUBÍK, Alois.
TRAIL and docosahexaenoic acid cooperate to induce HT-29 colon cancer cell death. Cancer Letters, OXFORD, ELSEVIER, Great Britain. ISSN 0304-3835, 2005.


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NAVRÁTILOVÁ, Jarmila - HORVÁTH, Viktor - LOJEK, Antonín - VOJTĚŠEK, Bořivoj - KOZUBÍK, Alois - ŠMARDA, Jan.
Využití průtokové cytometrie pro sledování proliferace a diferenciace monoblastů transformovaných onkogenem v-myb. In Analytická cytometrie III. Červenohorské sedlo : Česká společnost pro analytickou cytologii, 2005. ISBN 80-239-5155-6, pp. 150-151. 21.6.2005, Červenohorské sedlo.


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2004

VONDRÁČEK, J - CHRAMOSTOVÁ, K - KRČMÁŘ, P - KOZUBÍK, Alois - MACHALA, M.
Disruption of contact inhibition in rat liver epithelial cells by varrious types of AhR ligands. Organohalogen Compounds, The Nederlands. ISSN 1026-4892, 2004.


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VACULOVÁ, A - HOFMANOVÁ, Jiřina - SOUČEK, K - ANDĚRA, L - KOZUBÍK, Alois.
Ethanol acts as a potent agent sensitizing colon cancer cells to the TRAIL-induced apoptosis. FEBS Letters, The Nederlands. ISSN 0014-5793, 2004.


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HOFEROVÁ, Z - SOUČEK, K - HOFMANOVÁ, Jiřina - HOFER, M - CHRAMOSTOVÁ, K - FEDOROČKO, P - KOZUBÍK, Alois.
In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome. Cancer Investigation. ISSN 0735-7907, 2004.


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VONDRÁČEK, Jan - CHRAMOSTOVÁ, Kateřina - PLÍŠKOVÁ, Martina - BLÁHA, Luděk - BRACK, W. - KOZUBÍK, Alois - MACHALA, Miroslav.
Induction of arylhydrocarbon receptor-mediated and estrogen receptor-mediated activitites, and modulation of cell proliferation by dinaphthofurans. Environmental Toxicology and Chemistry, Pensacola, FL, USA, SETAC, USA. ISSN 0730-7268, 2004, vol. 23, no. -, pp. 2214-2220.


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TURÁNEK, J - KAŠNÁ, A - ZÁLUSKÁ, D - NEČA, J - KVARDOVÁ, V - KNÖTIGOVÁ, P - HORVÁTH, V - ŠINDLEROVÁ, L - KOZUBÍK, Alois - SOVA, P - KROUTIL, A - ŽÁK, F - MISTR, A.
New platinum (IV) complex with adamantylamine ligand as a promising anti-cancer drug: comparison of in vitro cytotoxic potential towards A2780/cisR cisplatin-resistent cell line within homologous series of platinum (IV) complexes. Anti-Cancer Drug Design, Oxford, UK, Oxford Press. ISSN 0266-9536, 2004.


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ŽÁK, František - TURÁNEK, Jaroslav - KROUTIL, Aleš - SOVA, Petr - MISTR, Adolf - POULOVÁ, Anna - MIKOLIN, Petr - ŽÁK, Zdirad - KAŠNÁ, Andrea - ZÁLUSKÁ, Dana - NEČA, Jiří - ŠINDLEROVÁ, Lenka - KOZUBÍK, Alois.
Platinum(V) Complex with Adamantylamine as Nonleaving Amine Group: Synthesis, Characterization, and in Vitro Antitumor Activity against a Panel of Cisplatin-Resistant Cancer Cell Lines. Journal Medicinal Chemistry, USA, USA, USA. ISSN 0022-2623, 2004, vol. 2004, no. 47, pp. 461-463.


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ŽÁK, František - TURÁNEK, Jaroslav - KROUTIL, Aleš - SOVA, Petr - MISTR, Adolf - POULOVÁ, Anna - MIKOLIN, Petr - ŽÁK, Zdirad - KAŠNÁ, Andrea - ZÁLUSKÁ, Dana - NEČA, Jiří - ŠINDLEROVÁ, Lenka - KOZUBÍK, Alois.
Platinum(V) Complex with Adamantylamine as Nonleaving Amine Group: Synthesis, Characterization, and in Vitro Antitumor Activity against a Panel of Cisplatin-Resistant Cancer Cell Lines. Journal Medicinal Chemistry, USA, USA, USA. ISSN 0022-2623, 2004, vol. 2004, no. 47, pp. 461-463.


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KOVAŘÍKOVÁ, M - HOFMANOVÁ, Jiřina - SOUČEK, K - KOZUBÍK, Alois.
The effects of TNF- and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status. Differentiation. ISSN 0301-4681, 2004.


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2003

FAJKUS, Jiří - BORSKÝ, Marek - KUNICKÁ, Zuzana - KOVAŘÍKOVÁ, Martina - DVOŘÁKOVÁ, Dana - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Changes in Telomerase Activity, Expression and Splicing in Response to Differentiation of Normal and Carcinoma Colon Cells. Anticancer Research, Athens, INT INST ANTICANCER RESEARCH, Greece. ISSN 0250-7005, 2003, vol. Neuveden, no. 23, pp. 1605-1612.


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ŠMARDA, Jan - BRYJA, Vítězslav - SEDLÁČEK, Jiří - ZAHRADNÍČKOVÁ, Eva - ŠEVČÍKOVÁ, Sabina - PACHERNÍK, Jiří - SOUČEK, Karel - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Lipoxygenase inhibitors enhance tumor suppressive effects of Jun proteins on v-myb-transformed monoblasts. Prostaglandins and other lipid mediators, New York (USA), Elsevier Science, USA. ISSN 0090-6980, 2003, vol. 72, no. 3-4, pp. 131-145.


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BRYJA, V - SEDLÁČEK, J - ŠEVČÍKOVÁ, S - ZAHRADNÍČKOVÁ, E - PACHERNÍK, J - SOUČEK, K - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - ŠMARDA, J.
Lipoxygenase inhibitors enhance tumor suppressive effects of Jun proteins on v-myb-transformed monoblasts BM2. Prostaglandins & Other Lipid Mediators. ISSN 1098-8823, 2003.


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HOFEROVÁ, Z - FEDOROČKO, P - HOFER, M - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois - ELIÁŠOVÁ, V.
Lipoxygenase inhibitors suppress proliferation of G5:113 fibrosarcoma cells in vitro but they have no anticancer activity in vivo. Neoplasma. ISSN 0028-2685, 2003.


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2002

PACHERNÍK, Jiří - JANÍK, R. - HOFMANOVÁ, Jiřina - BRYJA, Vítězslav - KOZUBÍK, Alois.
Conditions for gene transfection into the HL-60 human leukaemia cell line by electroporation. Folia Biologica. ISSN 0015-5500, 2002, vol. 48, p. 157-159.


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FAJKUS, Jiří - BORSKÝ, Marek - KUNICKÁ, Zuzana - KOVAŘÍKOVÁ, M. - DVOŘÁKOVÁ, Dana - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Changes in telomerase activity and expression in the process of butyrate-induced cell differentiation. Brno : D. Schweizer, K. Nasmyth, EMBO Workshop Genetics after the Genome, 2002. Neuveden.


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HOFMANOVÁ, Jiřina - VACULOVÁ, Alena - KOVAŘÍKOVÁ, Martina - ZADÁK, Zdeněk - KOZUBÍK, Alois.
Interaction of polyunsaturated fatty acids and sodium butyrate in human colon adenocarcinoma cells in vitro. In Abstract book ISAC XXI. International Congress. San Diego, USA : 2002. 1 p. May, 4-9, 2002, San Diego, USA.


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VACULOVÁ, Alena - HOFMANOVÁ, Jiřina - SOUČEK, Karel - KOZUBÍK, Alois.
Tumour necrosis factor-alpha-induced cell death in colon cancer cells. In The Third European Workshop on Cell Death. Spain : 2002. 1 p. February 23-28, 2002, Salobrena, Spain.


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2001

VONDRÁČEK, Jan - ŠTIKA, Jiří - SOUČEK, Karel - MINKSOVÁ, Kateřina - BLÁHA, Luděk - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells. European Journal of Pharmacology, Amsterdam, Elsevier Science B.V., The Nederlands. ISSN 0014-2999, 2001, vol. 424, no. 1, pp. 1-11.


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VONDRÁČEK, Jan - SHEARD, M.A. - KREJČÍ, Pavel - MINKSOVÁ, Kateřina - HOFMANOVÁ, Jiřina - KOZUBÍK, Alois.
Modulation of death receptor-mediated apoptosis in differentiating human myeloid leukemia HL-60 cells. Journal of Leukocyte Biology, New York, Society for Leukocyte Biology, USA. ISSN 0741-5400, 2001, vol. 69, no. 5, pp. 794-802.


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