Informace o publikaci
Specific conditions of tumor microenvironment enhance cytotoxicity of disulfiram, tetrathiomolybdate and wedelolactone to breast cancer and neuroblastoma cells
| Název česky | Specifický podmínky mikroprostředí nádoru zvyšují cytotoxicitu disulfiramu, tetrathiomolybdátu a wedelolaktonu na buňky nádoru prsu a neuroblastomu |
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| Autoři | |
| Rok publikování | 2013 |
| Druh | Konferenční abstrakty |
| Fakulta / Pracoviště MU | |
| Citace | |
| Popis | Our study was designed to analyze the effects of hypoxia, acidosis, and limited glucose supply to cytotoxicity of disulfiram, tetrathiomolybdate and wedelolactone to breast cancer and neuroblastoma cells. We found that cytotoxicity of these drugs can be strongly enhanced by manipulating tissue culture conditions that simulate the character of tumor microenvironment. |
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