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Diagnosis of Laryngeal Pemphigus Vulgaris Can Be Facilitated Using Advanced Endoscopic Methods

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STANIKOVA L FORMÁNEK Martin HURNÍK Pavel KANTOR P KOMÍNEK Pavel ZELENIK K

Rok publikování 2021
Druh Článek v odborném periodiku
Časopis / Zdroj Medicina-Lithuania
Citace
Doi http://dx.doi.org/10.3390/medicina57070686
Klíčová slova pemphigus vulgaris; larynx; Narrow Band Imaging (NBI); IMAGE1-S; enhanced contact endoscopy (ECE)
Popis Background: Isolated laryngeal pemphigus vulgaris (LPV) is rare; however, early diagnosis is crucial in determining its course and prognosis. This paper aims to describe mucosal vascular changes typical for LPV using advanced endoscopic methods, which include Narrow Band Imaging (NBI), IMAGE1-S video-endoscopy and enhanced contact endoscopy (ECE). Materials and Methods: Retrospective analysis of all laryngeal mucosal lesion examined using advanced endoscopic methods during 2018-2020 at tertiary hospital was performed. Results: Videolaryngoscopy examination records of 278 patients with laryngeal mucosal lesions were analyzed; three of them were diagnosed with LPV. Epithelial vascularization of LPV included specific pattern. Intraepithelial papillary capillary loops were symmetrically stratified and were organized into "contour-like lines". This specific vascularization associated with LPV were different from other laryngeal mucosal pathologies. Conclusions: Using advanced endoscopic methods supports early diagnosis of LPV and accelerate the diagnosis and treatment.

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