Informace o publikaci
The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4
| Autoři | |
|---|---|
| Rok publikování | 2021 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Stem Cell Reviews and Reports |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://link.springer.com/article/10.1007/s12015-021-10225-8 |
| Doi | http://dx.doi.org/10.1007/s12015-021-10225-8 |
| Klíčová slova | Stem cell; iPSCs; SoxE; Sox9; KIX; CBP; MED15 |
| Popis | Somatic cells can be reprogrammed by the Yamanaka factors Oct4, Sox2, Myc and Klf4 into pluripotent stem cells. Previously, we have identified the activation domain 9aaTAD in the related SP, KLF and SOX activators. In this study, we searched for the 9aaTAD domains in Yamanaka factors, which are activators of transcription. |
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