Informace o publikaci

Patient-reported symptoms are a more reliable predictor of the societal burden compared to established physician-reported activity indices in inflammatory bowel disease: a cross-sectional study

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DECKER Barbora TUZIL Jan LUKAS Milan CERNA Karin BORTLIK Martin VELACKOVA Barbora PILNACKOVA Barbora DOLEŽAL Tomáš

Rok publikování 2023
Druh Článek v odborném periodiku
Časopis / Zdroj Expert Review of Gastroenterology & Hepatology
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://www.tandfonline.com/doi/full/10.1080/17474124.2023.2161047
Doi http://dx.doi.org/10.1080/17474124.2023.2161047
Klíčová slova absenteeism; Crohn’s disease; out-of-pocket costs; presenteeism; productivity costs; ulcerative colitis
Přiložené soubory
Popis Background The societal burden of inflammatory bowel diseases (IBD) is not well documented, and further studies are needed to quantify the costs of the disease state. Thus, the aim was to estimate the societal burden and identify its predictors. Methods A cross-sectional questionnaire-based study complemented by objective data from patient medical records was performed for patients with Crohn’s disease (CD) and ulcerative colitis (UC). Results We analyzed data from 161 patients (CD: 102, UC: 59). The overall work impairment reached 15.4%, 11.2% vs. 28.8% without/with self-reported symptoms (p = 0.006). Daily activity impairment was 19.3%, 14.1% vs. 35.6% (p < 0.001). The disability pension rate was 28%, 23% vs. 44% (p = 0.012). The total productivity loss due to absenteeism, presenteeism, and disability amounted to 7,673 €/patient/year, 6,018 vs. 12,354 €/patient/year (p = 0.000). Out-of-pocket costs amounted to 562 €/patient/year, 472 vs. 844 €/patient/year (p = 0.001). Self-reported symptoms were the strongest predictor of costs (p < 0.001). Conclusion We found a high societal burden for IBD and a significant association between patient-reported disease symptoms and work disability, daily activity impairment, disability pensions, and out-of-pocket costs. Physician-reported disease activity is not a reliable predictor of costs except for out-of-pocket expenses.
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