Mgr. Marek Šebesta, Ph.D.
Senior researcher, Richard Štefl Research Group
Office: bldg. C04/229
Kamenice 753/5
625 00 Brno
Phone: | +420 549 49 7927 |
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E‑mail: |
social and academic networks: |
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Total number of publications: 17
2023
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Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor
Nucleic Acids Research, year: 2023, volume: 51, edition: 6, DOI
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The phosphorylated trimeric SOSS1 complex and RNA polymerase II trigger liquid-liquid phase separation at double-strand breaks
Cell Reports, year: 2023, volume: 42, edition: 12, DOI
2022
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Cryo-EM reveals the structural basis for the regulatory function of HEL1 domain in vertebrate DICERs
Year: 2022, type: Appeared in Conference without Proceedings
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Structural and functional basis of mammalian microRNA biogenesis by Dicer
Molecular Cell, year: 2022, volume: 82, edition: 21, DOI
2021
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PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Nature Communications, year: 2021, volume: 12, edition: 1, DOI
2020
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Structural Characterization of the Interaction Between BRCA1-BARD1 and RNA Polymerase II
Year: 2020, type: Conference abstract
2017
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A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance
Nucleic Acids Research, year: 2017, volume: 45, edition: 6, DOI
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Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains
Nucleic Acids Research, year: 2017, volume: 45, edition: 1, DOI
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Role of PCNA and RFC in promoting Mus81-complex activity
BMC BIOLOGY, year: 2017, volume: 15, edition: 90, DOI
2016
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The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis
Nucleic Acids Research, year: 2016, volume: 44, edition: 7, DOI