prof. Mgr. Vítězslav Bryja, Ph.D.

2026

• Casein kinase 1δ/ε inhibition suppresses CLL proliferation through cell-intrinsic and microenvironmental mechanisms

  MIKULOVÁ Antónia PLEŠINGEROVÁ Hana CHORVÁTOVÁ Michaela KEBKOVÁ Pavlína BARTOŠÍKOVÁ Jana PROCHÁZKOVÁ SCHRUMPFOVÁ Petra VERNER Jan MULIDRÁN Dominik ČADA Štěpán VONDÁLOVÁ BLANÁŘOVÁ Olga KOLČÁKOVÁ Nela LOJA Tomáš KURUCOVÁ Terézia HOFERKOVÁ Eva TICHÝ Boris KOTAŠKOVÁ Jana MRÁZ Marek KUBALA Lukáš JANOVSKÁ Pavlína BRYJA Vítězslav

  Article in Periodical

  HemaSphere, year: 2026, volume: 10, edition: 3, DOI

• Unraveling the Transcription Factor Code of Odontoblast Differentiation

  LAVICKÝ Josef GONZÁLEZ LÓPEZ Marcos CHOCHOLA Václav KOMPANÍKOVÁ Petra RAKULTSEV Vladislav RAŠKA Jan WINCHESTER E Wentworth TUAIMA Haneen Riadh Ali PEŠKOVÁ Lucie VERNER Jan ŠVANDOVÁ Eva BUCHTOVÁ Marcela COTNEY J. BRYJA Vítězslav BOHAČIAKOVÁ Dáša BÁRTA Tomáš KŘIVÁNEK Jan

  Article in Periodical

  Journal of Dental Research, year: 2026, volume: 105, edition: 2, DOI

2025

• A class III ligand oscillates between internal and terminal binding modes as it engages with the Dishevelled PDZ domain

  KUMAR Jitender MICKA Miroslav KOMÁREK Jan KLUMPLER Tomáš BYSTRÝ Vojtěch SPRANGERS Remco BARINKA Cyril BRYJA Vítězslav TRIPSIANES Konstantinos

  Article in Periodical

  Structure, year: 2025, volume: 33, edition: 8, DOI

• Analysis of AML cells in vitro: Sensitivity to CK1 inhibition vs. genetic background

  PLEŠINGEROVÁ Hana PRIŠTICOVÁ Ingrid PROCHÁZKOVÁ Petra ČULEN Martin BUŠA Daniel SCHEER Alexander MAYER Jiří PARUCH Kamil BRYJA Vítězslav JANOVSKÁ Pavlína

  Conference abstract

  Year: 2025, type: Conference abstract

• Analysis of primary AML cells sensitivity to casein kinase 1 inhibitor in vitro

  PLEŠINGEROVÁ Hana PRIŠTICOVÁ Ingrid PROCHÁZKOVÁ Petra ČULEN Martin BUŠA Daniel MAYER Jiří PARUCH Kamil BRYJA Vítězslav JANOVSKÁ Pavlína

  Conference abstract

  Year: 2025, type: Conference abstract

• CK1α-dependent phosphorylation of NOTCH1 is required for transcriptional activity of N1ICD

  TURETTI Fabio AGOSTINI MAIA Lorena HAJŠMANOVÁ Hana GYBEĽ Tomáš DOKOUPIL Marek BRYJA Vítězslav HARNOŠ Jakub MAŠEK Jan

  Conference abstract

  Year: 2025, type: Conference abstract

• Comparative Analysis of Migration in Healthy Human B Cell Populations

  KOLČÁKOVÁ Nela ČADA Štěpán MIKULOVÁ Antónia PAVLOVÁ Šárka KOTAŠKOVÁ Jana BRYJA Vítězslav

  Conference abstract

  Year: 2025, type: Conference abstract

• Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε

  HAAG Adrian NEMEC Vaclav JANOVSKÁ Pavlína BARTOŠÍKOVÁ Jana ADHIKARI Bikash MUELLER Juliane SCHWALM Martin P ČADA Štěpán OHMAYER Uli DAUB Henrik KIM Yeojin BORN Florian WOLF Elmar BRYJA Vítězslav KNAPP Stefan

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2025, volume: 68, edition: 1, DOI

• Challenges in flow cytometric analysis of B cell populations co-cultured with stromal feeder cells

  VONDÁLOVÁ BLANÁŘOVÁ Olga MIKULOVÁ Antónia PLEŠINGEROVÁ Hana MRÁZ Marek KOTAŠKOVÁ Jana BRYJA Vítězslav JANOVSKÁ Pavlína

  Conference abstract

  Year: 2025, type: Conference abstract

• Mechanism of regulation of lymphoid cell migration persistence by casein kinase 1

  ČADA Štěpán GÖMÖRYOVÁ Kristína MARTINKOVÁ Petra BARTOŠÍKOVÁ Jana NĚMEC Václav HAAG Adrian POTĚŠIL David MODRIANSKY Branislav ZDRÁHAL Zbyněk KNAPP Stefan BRYJA Vítězslav

  Conference abstract

  Year: 2025, type: Conference abstract