Mgr. Dalibor Blažek, Ph.D.

2020

• Identification of CDK11 interactome

  HLUCHÝ Milan POTĚŠIL David ZDRÁHAL Zbyněk BLAŽEK Dalibor

  Conference abstract

  Year: 2020, type: Conference abstract

2019

• CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes

  CHIRACKAL MANAVALAN Anil Paul PILAŘOVÁ Květa KLUGE Michael BARTHOLOMEEUSEN Koen RÁJECKÝ Michal OPPELT Jan KHIRSARIYA PrashantKumar PARUCH Kamil KREJČÍ Lumír FRIEDEL Caroline C BLAŽEK Dalibor

  Peer-reviewed scientific article

  EMBO reports, year: 2019, volume: 20, edition: 9, DOI

2018

• CDK12 kinase activity controls G1/S progression by regulating optimal transcription of core DNA replication genes

  CHIRACKAL MANAVALAN Anil Paul PILAŘOVÁ Květa KLUGE M. BARTHOLOMEEUSEN Koen OPPELT Jan KHIRSARIYA PrashantKumar PARUCH Kamil KREJČÍ Lumír FRIEDEL C. BLAŽEK Dalibor

  Conference abstract

  Year: 2018, type: Conference abstract

2016

• Structural and Functional Analysis of the Cdk13/Cyclin K Complex

  GREIFENBERG Ann Katrin HÖNIG Dana PILAŘOVÁ Květa DÜSTER Robert BARTHOLOMEEUSEN Koen BOSKEN Christian A. ANAND Kanchan BLAŽEK Dalibor GEYER Matthias

  Peer-reviewed scientific article

  Cell Reports, year: 2016, volume: 14, edition: 2, DOI

• The CD8+cell non-cytotoxic antiviral response affects RNA polymerase II-mediated human immunodeficiency virus transcription in infected CD4+cells

  BLAŽEK Dalibor TEQUE Fernando MACKEWICZ Carl PETERLIN Matija LEVY Jay A.

  Peer-reviewed scientific article

  Journal of General Virology, year: 2016, volume: 97, edition: January, DOI

2015

• Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.

  EKUMI Kingsley M. PACULOVÁ Hana LENASI Tina POSPÍCHALOVÁ Vendula BOESKEN Christian A. RYBAŘÍKOVÁ Jana BRYJA Vítězslav GEYER Matthias BLAŽEK Dalibor BARBORIC Matjaz

  Peer-reviewed scientific article

  Nucleic Acids Research, year: 2015, volume: 43, edition: 5, DOI

2014

• The structure and substrate specificity of human Cdk12/Cyclin K

  BÖSKEN Christian A. FARNUNG Lucas HINTERMAIR Corinna SCHACHTER Miriam Merzel VOGEL- BACHMAYR Karin BLAŽEK Dalibor ANAND Kanchan FISHER Robert P. EICK Dirk GEYER Matthias

  Peer-reviewed scientific article

  NATURE COMMUNICATIONS, year: 2014, volume: 5, edition: 3505, DOI

• Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway

  ŠMERDOVÁ Lenka SVOBODOVÁ Jana KABÁTKOVÁ Markéta KOHOUTEK Jiří BLAŽEK Dalibor MACHALA Miroslav VONDRÁČEK Jan

  Peer-reviewed scientific article

  Carcinogenesis, year: 2014, volume: 35, edition: 11, DOI

2012

• Cyclin K goes with Cdk12 and Cdk13

  KOHOUTEK Jiří BLAŽEK Dalibor

  Peer-reviewed scientific article

  Cell Division, year: 2012, volume: 7, edition: 12, DOI

• The cyclin K/Cdk12 complex An emerging new player in the maintenance of genome stability

  BLAŽEK Dalibor

  Peer-reviewed scientific article

  Cell Cycle, year: 2012, volume: 11, edition: 6, DOI