Mgr. Jan Ryneš, Ph.D.

2025

• In-cell NMR spectroscopy of nucleic acids: Basic concepts, practical aspects, and applications

  TRANTÍRKOVÁ Silvie HARNOŠ Jakub RYNEŠ Jan ZLÍNSKÁ Vladimíra TRANTÍREK Lukáš

  Article in Periodical

  Progress in Nuclear Magnetic Resonance Spectroscopy, year: 2025, volume: 148-149, edition: August-October, DOI

• Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models

  RYNEŠ Jan IŠTVÁNKOVÁ Eva KRAFČÍKOVÁ Michaela LUCHINAT Enrico BARBIERI Letizia BANCI Lucia KAMARÝTOVÁ Kristýna LOJA Tomáš FAFÍLEK Bohumil RICO LLANOS Gustavo KREJČÍ Pavel MACUREK Libor TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

  Article in Periodical

  Communications Biology, year: 2025, volume: 8, edition: 1, DOI

• Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer

  ZLÍNSKÁ Vladimíra FEKETOVÁ Zuzana CZYREK Aleksandra Anna CHUDZIAN Julia ZIVKOVIC Martina Lenarcic URSACHI Vlad-Constantin DUDEJA Pooja FAFÍLEK Bohumil RYNEŠ Jan RICO LLANOS Gustavo KOUDELKA Adolf ROY Tanaya BIADUN Martyna RAŠKOVÁ Vendula SVOZILOVÁ Kateřina STROBLOVÁ Michaela KRZYSCIK Mateusz HRISTOVA Kalina KROWARSCH Daniel TRANTÍRKOVÁ Silvie ZAKRZEWSKA Malgorzata TRANTÍREK Lukáš KREJČÍ Pavel

  Article in Periodical

  MOLECULAR THERAPY-NUCLEIC ACIDS, year: 2025, volume: 36, edition: 1, DOI

2024

• A sodium/potassium switch for G4-prone G/C-rich sequences

  LUO Yu LENARČIČ ŽIVKOVIC Martina WANG Jiawei RYNEŠ Jan TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš VERGA Daniela MERGNY Jean-Louis

  Article in Periodical

  Nucleic acids research, year: 2024, volume: 52, edition: 1, DOI

• In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells

  VÍŠKOVÁ Pavlína IŠTVÁNKOVÁ Eva RYNEŠ Jan DŽATKO Šimon LOJA Tomáš LENARČIČ ŽIVKOVIC Martina RIGO Riccardo EL-KHOURY Roberto SERRANO-CHACON Israel DAMHA Masad J GONZALEZ Carlos MERGNY Jean-Louis TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

  Article in Periodical

  Nature Communications, year: 2024, volume: 15, edition: 1, DOI

2023

• A thermosensitive gel matrix for bioreactor-assisted in-cell NMR of nucleic acids and proteins

  DZUROV Matej POSPÍŠILOVÁ Šárka KRAFČÍKOVÁ Michaela TRANTÍREK Lukáš VOJTOVÁ Lucy RYNEŠ Jan

  Article in Periodical

  Journal of biomolecular NMR, year: 2023, volume: 77, edition: 5-6, DOI

2020

• Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA

  ŠKOLÁKOVÁ Petra BADRI Zahra TRANTÍRKOVÁ Silvie RYNEŠ Jan ŠPONER Jiří FOJTOVÁ Miloslava FAJKUS Jiří MAREK Radek VORLÍČKOVÁ Michaela MERGNY Jean-Louis TRANTÍREK Lukáš

  Article in Periodical

  BBA - General Subjects, year: 2020, volume: 1864, edition: 9, DOI

• Elucidation of protein interactions necessary for the maintenance of the BCR-ABL signaling complex

  GREGOR Tomáš BOSÁKOVÁ Michaela NITĂ Alexandru POOVAKULATHU ABRAHAM Sara FAFÍLEK Bohumil ČERNOHORSKÁ Nicole RYNEŠ Jan TRANTÍRKOVÁ Silvie ŽÁČKOVÁ Daniela MAYER Jiří TRANTÍREK Lukáš KREJČÍ Pavel

  Article in Periodical

  Cellular and molecular life sciences, year: 2020, volume: 77, edition: 19, DOI

2019

• Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1

  HARNOŠ Jakub CANIZAL M.C.A. JURÁSEK Miroslav KUMAR Jitender HOLLER Cornelia SCHAMBONY Alexandra HANÁKOVÁ Kateřina BERNATÍK Ondřej ZDRÁHAL Zbyněk GÖMÖRYOVÁ Kristína GYBEĽ Tomáš RADASZKIEWICZ Tomasz Witold KRAVEC Marek TRANTÍREK Lukáš RYNEŠ Jan DAVE Zankruti FERNANDEZ-LLAMAZARES Ana Iris VÁCHA Robert TRIPSIANES Konstantinos HOFFMANN Carsten BRYJA Vítězslav

  Article in Periodical

  Nature Communications, year: 2019, volume: 10, edition: APR 18 2019, DOI

2018

• Advances in the cellular structural biology of nucleic acids

  GIASSA Ilektra-Chara RYNEŠ Jan FESSL T. TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

  Article in Periodical

  FEBS LETTERS, year: 2018, volume: 592, edition: 12, DOI