prof. RNDr. Jan Vondráček, Ph.D.

2023

• Benzo[b]naphtho[d]thiophenes and naphthylbenzo[b]thiophenes: Their aryl hydrocarbon receptor-mediated activities and environmental presence

  MARVANOVÁ Soňa PĚNČÍKOVÁ Kateřina PÁLKOVÁ Lenka CIGANEK Miroslav PETRÁŠ Jiří LNĚNIČKOVÁ Anna VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  SCIENCE OF THE TOTAL ENVIRONMENT, year: 2023, DOI

2021

• Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells

  HOFMANOVÁ Jiřina SLAVIK Josef CIGANEK Miroslav OVESNÁ Petra TYLICHOVA Zuzana KARASOVÁ Martina ZAPLETAL Ondrej STRAKOVA Nicol PROCHAZKOVA Jirina BOUCHAL Jan KOLAR Zdenek EHRMANN Jiri LEVKOVA Monika HUSKOVA Zlatka SKALICKY Pavel KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 13, DOI

2020

• Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells

  VONDRÁČEK Jan PĚNČÍKOVÁ Kateřina CIGANEK Miroslav PIVNIČKA Jakub KARASOVÁ Martina HÝŽĎALOVÁ Martina STRAPÁČOVÁ Simona PÁLKOVÁ Lenka NEČA Jiří MATTHEWS Jason LOM Michal Vojtíšek TOPINKA Jan MILCOVÁ Alena MACHALA Miroslav

  Article in Periodical

  ENVIRONMENTAL POLLUTION, year: 2020, DOI

2019

• Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models

  ZAPLETAL Ondřej PROCHÁZKOVÁ Jiřina DUBEC Vít HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  Toxicology, year: 2019, volume: 412, edition: JAN, DOI

• FUNCTIONAL ROLE OF AHR IN DIOXIN-MEDIATED DISRUPTION OF APOPTOSIS CONTROL IN A HUMAN MODEL OF ADULT LIVER PROGENITORS?

  KRKOŠKA Martin SVOBODOVÁ Jana KABÁTKOVÁ Markéta HYRŠLOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2019, type: Conference abstract

• In vitro and in vivo genotoxicity of oxygenated polycyclic aromatic hydrocarbons

  MCCARRICK Sarah CUNHA Virginia ZAPLETAL Ondřej VONDRÁČEK Jan DREIJ Kristian

  Article in Periodical

  Environmental Pollution, year: 2019, volume: 246, edition: MAR 2019, DOI

• n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models

  TYLICHOVÁ Zuzana NECA Jiri TOPINKA Jan MILCOVA Alena HOFMANOVÁ Jiřina KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Food and Chemical Toxicology, year: 2019, volume: 124, edition: FEB 2019, DOI

2018

• Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands

  PROCHÁZKOVÁ Jiřina STRAPÁČOVÁ Simona SVRŽKOVÁ Lucie ANDRYSÍK Zdeněk HYZDALOVA Martina HRUBÁ Eva PĚNČÍKOVÁ Kateřina LIBALOVA H TOPINKA J KLÉMA Jiří ESPINOSA JM VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Toxicology Letters, year: 2018, volume: 292, DOI

• Aryl Hydrocarbon Receptor-Dependent Metabolism Plays a Significant Role in Estrogen-Like Effects of Polycyclic Aromatic Hydrocarbons on Cell Proliferation

  HYZDALOVA M. PIVNIČKA Jakub ZAPLETAL Ondřej VAZQUEZ-GOMEZ G. MATTHEWS J. NEČA Jiří PĚNČÍKOVÁ Kateřina MACHALA M. VONDRÁČEK Jan

  Article in Periodical

  Toxicological sciences, year: 2018, volume: 165, edition: 2, DOI

• Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro

  PĚNČÍKOVÁ Kateřina BRENEROVÁ Petra SVRŽKOVÁ Lucie HRUBÁ Eva PÁLKOVÁ Lenka VONDRÁČEK Jan HANS-JOACHIM Lehmler MACHALA Miroslav

  Article in Periodical

  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, year: 2018