2021

• Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells

  HOFMANOVÁ Jiřina SLAVIK Josef CIGANEK Miroslav OVESNÁ Petra TYLICHOVA Zuzana KARASOVÁ Martina ZAPLETAL Ondrej STRAKOVA Nicol PROCHAZKOVA Jirina BOUCHAL Jan KOLAR Zdenek EHRMANN Jiri LEVKOVA Monika HUSKOVA Zlatka SKALICKY Pavel KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  International Journal of Molecular Sciences, year: 2021, volume: 22, edition: 13, DOI

2019

• Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models

  ZAPLETAL Ondřej PROCHÁZKOVÁ Jiřina DUBEC Vít HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  Toxicology, year: 2019, volume: 412, edition: JAN, DOI

• FUNCTIONAL ROLE OF AHR IN DIOXIN-MEDIATED DISRUPTION OF APOPTOSIS CONTROL IN A HUMAN MODEL OF ADULT LIVER PROGENITORS?

  KRKOŠKA Martin SVOBODOVÁ Jana KABÁTKOVÁ Markéta HYRŠLOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2019, type: Conference abstract

• In vitro and in vivo genotoxicity of oxygenated polycyclic aromatic hydrocarbons

  MCCARRICK Sarah CUNHA Virginia ZAPLETAL Ondřej VONDRÁČEK Jan DREIJ Kristian

  Article in Periodical

  Environmental Pollution, year: 2019, volume: 246, edition: MAR 2019, DOI

• n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models

  TYLICHOVÁ Zuzana NECA Jiri TOPINKA Jan MILCOVA Alena HOFMANOVÁ Jiřina KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Food and Chemical Toxicology, year: 2019, volume: 124, edition: FEB 2019, DOI

2018

• Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands

  PROCHÁZKOVÁ Jiřina STRAPÁČOVÁ Simona SVRŽKOVÁ Lucie ANDRYSÍK Zdeněk HYZDALOVA Martina HRUBÁ Eva PĚNČÍKOVÁ Kateřina LIBALOVA H TOPINKA J KLÉMA Jiří ESPINOSA JM VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Toxicology Letters, year: 2018, volume: 292, DOI

• Aryl Hydrocarbon Receptor-Dependent Metabolism Plays a Significant Role in Estrogen-Like Effects of Polycyclic Aromatic Hydrocarbons on Cell Proliferation

  HYZDALOVA M. PIVNIČKA Jakub ZAPLETAL Ondřej VAZQUEZ-GOMEZ G. MATTHEWS J. NEČA Jiří PĚNČÍKOVÁ Kateřina MACHALA M. VONDRÁČEK Jan

  Article in Periodical

  Toxicological sciences, year: 2018, volume: 165, edition: 2, DOI

• Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells.

  TYLICHOVÁ Zuzana SLAVÍK Josef CIGANEK Miroslav OVESNÁ Petra KRČMÁŘ Pavel STRAKOVÁ Nicol MACHALA Miroslav KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan

  Article in Periodical

  J Cell Biochem, year: 2018, volume: 119, edition: 6, DOI

• INHIBITION OF P300/CBP REDUCES CYP1A1 INDUCTION IN CANCER CELL MODELS DERIVED FROM THE LIVER OR COLON EPITHELIUM

  KRKOŠKA Martin SVOBODOVÁ Jana ZAPLETAL Ondřej KARASOVÁ Martina HYRŠLOVÁ VACULOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2018, type: Conference abstract

2017

• Activation of autophagy and PPAR gamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation

  TYLICHOVÁ Zuzana STRAKOVÁ Nicol VONDRÁČEK Jan VACULOVA A.H. KOZUBÍK Alois HOFMANOVÁ Jiřina

  Article in Periodical

  JOURNAL OF NUTRITIONAL BIOCHEMISTRY, year: 2017, volume: 39, edition: January, DOI