doc. MUDr. Alena Damborská, Ph.D.

Curriculum Vitae

Person Identification

• Alena Damborská, MD, Ph.D. ORCID iD 0000-0002-9714-7441
  http:/ / psychiatrie.med.muni.cz/
  https://www.ceitec.eu/ceitec-mu/multi-modal-and-functional-neuroimaging/rg65
  https://www.researchgate.net/profile/Alena_Damborska

Current Positions

• Senior Staff Scientist (since 05/2019)
  Multi-modal and Functional Neuroimaging Research Group, Brain and Mind Research Program, Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic
  
  
• Assistant Professor (since 05/2019)
  Electrophysiology Research Group, Department of Psychiatry, Masaryk University, Brno, Czech Republic
  
  
• Psychiatrist in training (since 05/2019)
  Department of Psychiatry, University Hospital Brno, Brno, Czech Republic
  

Previous Positions

• 05/2017 – 04/2019: Marie Skłodowska-Curie Action Post-Doctoral Research Fellow, Faculty of Medicine, Department of Basic Neurosciences, University of Geneva, Switzerland
• 09/2015 – 04/2017 Psychiatrist in training, Department of Psychiatry, University Hospital Brno, Brno, Czech Republic
• 05/2015 – 04/2017: Assistant Professor, Department of Psychiatry, Masaryk University, Brno, Czech Republic
• 06/2012 – 08/2015: Assistant Professor, Department of Physiology, Masaryk University, Brno, Czech Republic
• 01/2011 – 04/2017: Researcher, Multi-modal and Functional Neuroimaging Research Group, Brain and Mind Research Program, CEITEC, Masaryk University, Brno, Czech Republic
• 09/2007 – 05/2012: Assistant, Department of Physiology, Masaryk University, Brno, Czech Republic
• 03/2002 - 08/2007: Career break - maternity leave (two children)
• 03/1999 – 02/2002: Assistant, Department of Physiology, Masaryk University, Brno, Czech Republic
• 09/1997 - 02/1999: Pathologist in training, Department of Pathology, University Hospital Brno, Czech Republic

Education

• 2016 Functional specialization in electroencephalography – exam guaranteed by Czech Society for Clinical Neurophysiology
• 2012 Ph.D. in Physiology and Pathological Physiology, Faculty of Medicine, Masaryk University, Czech Republic; Thesis: Event-related potentials registered intracerebrally during visual oddball task in human, supervisor: Prof. MUDr. Miloslav Kukleta, CSc.
• 2010-2011 PREFECT course - Organization, Management and Project Management of Research and Development
• 1997 Master M.D., General Medicine/ Faculty of Medicine/ Masaryk
  University/ Czech Republic

Teaching activities

• Since 2019: Supervision of a doctoral student of Neurosciences
• Since 2017: Supervisin of Master students of General Medicine within the Undergraduate Program for Motivated Students of Medicine with Extended Scientific Training
• 2013 - 2017: Supervision of Master students of General Medicine in their Individual Projects
• Since 2016: Lectures on Scientific and Educational Seminars guaranteed by the Czech Medical Chamber, Department of Psychiatry, Medical Faculty, Masaryk University, Czech Republic
• 1999 – 2015: Tutorials, practicals, and lectures on Physiology and Neuroscience, Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic

Research Focus

• Dr. Damborská is an expert in mapping human brain, whose research focuses on electrophysiological correlates of cognitive functions and functional brain abnormalities in psychiatric disorders. This builds upon her medical backgrounds and expertise in intracranial and high density scalp electroencephalography. Recently, Dr. Damborská conducted a study on large-scale brain neuronal networks in depressive patients. Currently her research is aimed at resting-state cortico-subcortical functional coupling of the human brain and electrophysiological biomarkers of responsivness to electroconvulsive therapy and pharmacotherapy in affective disorders.
  Some of the specific areas of current interest include also study on electrophysiological correlates of responsivness to dialectical behavioral therapy in borderline personality disorder.

Research Projects

• 2020 - 2023 - Work package leader- Neural mechanisms of dialectical behavioral therapy in patinets with borderline personality disorder (NU20-04-00410)
  Sponsor: Ministry of Health of the CR / Ministry of Health Research Programme 2020 - 2026
  
• 2017 – 2019 - Principal Investigator - Deep brain targets for neurostimulation in affective disorders (739939) https://cordis.europa.eu/project/id/739939
  Sponsor: European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Action - Individual Fellowships (Call H2020/MSCA/IF/2016)
  
• 2016 – 2019: Work package leader- Modulation of functional connectivity of the large scale cortical networks by deep brain stimulation of subthalamic nucleus (16-33798A)
  Sponsor: Ministry of Health of the Czech Republic
  
• 2015 – 2018: Work package leader - Impulsivity phenotypes and their clinical impact in neuropsychiatric disorders (15-30062A)
  Sponsor: Ministry of Health of the Czech Republic
  
• 1999 – 2002: Member of the team - Plasticity of Regulatory Mechanisms of the Central Nervous Systems (MSM141100001)
  Sponsor: Ministry of Education, Youth and Sports of the Czech Republic

Internships

• 04/2019: Secondment during the Marie Skłodowska-Curie Action at the Mood Disorder Unit, Department of Psychiatry and Mental Health, Service of Psychiatric Specialties, Geneva University Hospital, Geneva, Switzerland; mentor: Prof. Alexandre Dayer
• 05/2017 – 04/2019: Marie Skłodowska-Curie Action Post-Doctoral Research Fellow, Faculty of Medicine, Department of Basic Neurosciences, University of Geneva, Switzerland; mentor: Prof. Christoph M. Michel
• 09/2014 - 11/2014: Post-Doctoral Research Fellow, Functional Brain Mapping laboratory, Geneva University Hospital, Geneva, Switzerland; supervisor: Prof. Christoph M. Michel
• 04/2001 - 06/2001: Doctoral Research Fellow, Serviço de Neurofisiologia, Hospital Santo António/Centro Hospitalar do Porto, Oporto, Portugal; supervisor: Prof. António Martins da Silva

Institutional Responsibilities

• 2015 – 2017: Member of Advisory committee for organization of Masaryk University Life Sciences Seminar Series sponsored by CEITEC and ICRC
• 2012 – 2017 Organizer of the Internal Seminars on Individual projects of master students, Department of Physiology/Department of Psychiatry, Faculty of Medicine, Masaryk University, Czech Republic

Reviewing Activities

• Reviewer for journals: Scientific Reports, Brain Topography, Behavioural Brain Research, Neuropsychologia, Activitas Nervosa Superior, Electronics, Journal of Personalised Medicine, PLOS One
• 2017 Project Reviewer for Czech Health Research Council/ Czech Republic
• Member of Editorial Board for the journal Activitas Nervosa Superior (Springer)
• Reviewer of PhD. and Bc. theses for Comenius University, Bratislava, Slovakia and Masaryk University, Brno, Czech Republic

Major Publications

• KOENIG, Thomas, Sarah DIEZIG, Sahana N KALBURGI, Elena ANTONOVA, Fiorenzo ARTONI, Lucie BRECHET, Juliane BRITZ, Pierpaolo CROCE, Anna CUSTO, Alena DAMBORSKÁ, Camila DEOLINDO, Markus HEINRICHS, Tobias KLEINERT, Zhen LIANG, Michael M MURPHY, Kyle NASH, Chystopher NEHANIV, Bastian SCHILLER, Una SMAILOVIC, Povilas TARAILIS, Miralena I TOMESCU, Eren TOPLUTAS, Federica VELLANTE, Anthony ZANESCO, Filippo ZAPPASODI, Qihong ZOU a Christoph M MICHEL. EEG-Meta-Microstates: Towards a more objective use of resting-state EEG microstate findings across studies. BRAIN TOPOGRAPHY. UNITED STATES: SPRINGER, 2024, s. 1-14. ISSN 0896-0267. Dostupné z: https://dx.doi.org/10.1007/s10548-023-00993-6. URL info
• CHIVU, Alina, Simona A PASCAL, Alena DAMBORSKÁ a Miralena I TOMESCU. EEG Microstates in Mood and Anxiety Disorders: A Meta-analysis. BRAIN TOPOGRAPHY. DORDRECHT: SPRINGER, 2024, s. 1-12. ISSN 0896-0267. Dostupné z: https://dx.doi.org/10.1007/s10548-023-00999-0. URL info
• TRENADO, Carlos, Ignacio MENDEZ-BALBUENA, Alena DAMBORSKÁ, Amir HUSSAIN, Mufti MAHMUD a Mohammad R DALIRI. Editorial: The new frontier in brain network physiology: from temporal dynamics to the principles of integration in physiological brain networks. In Frontiers in Computational Neuroscience. FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2023, s. 1242834. ISSN 1662-5188. Dostupné z: https://dx.doi.org/10.3389/fncom.2023.1242834. URL info
• BARTEČKŮ, Elis, Jana HOŘÍNKOVÁ, Pavel KŘENEK, Alena DAMBORSKÁ, Josef TOMANDL, Marie TOMANDLOVÁ, Jan KUČERA, Jana KUČEROVÁ a Julie DOBROVOLNÁ. Osteocalcin levels decrease during the treatment of an acute depressive episode. Frontiers in Psychiatry. LAUSANNE: FRONTIERS MEDIA SA, 2022, roč. 13, August 2022, s. 1-8. ISSN 1664-0640. Dostupné z: https://dx.doi.org/10.3389/fpsyt.2022.893012. URL info
• DAMBORSKÁ, Alena, Martin LAMOŠ, D. BRUNET, S. VULLIEMOZ, Martina BOČKOVÁ, Barbora DEUTSCHOVÁ, Marek BALÁŽ a Ivan REKTOR. Resting-State Phase-Amplitude Coupling Between the Human Subthalamic Nucleus and Cortical Activity: A Simultaneous Intracranial and Scalp EEG Study. BRAIN TOPOGRAPHY. DORDRECHT: SPRINGER, 2021, roč. 34, č. 3, s. 272-282. ISSN 0896-0267. Dostupné z: https://dx.doi.org/10.1007/s10548-021-00822-8. URL info
• DAMBORSKÁ, Alena, Eliška HONZÍRKOVÁ, Elis BARTEČKŮ, Jana HOŘÍNKOVÁ, Sylvie FEDOROVÁ, Šimon ONDRUŠ, Christoph M. MICHEL a Maria RUBEGA. Altered directed functional connectivity of the right amygdala in depression: high-density EEG study. Scientific Reports. London: Nature Publishing Group, 2020, roč. 10, č. 1, s. 1-14. ISSN 2045-2322. Dostupné z: https://dx.doi.org/10.1038/s41598-020-61264-z. URL info
• DROBISZ, Dominik a Alena DAMBORSKÁ. Deep brain stimulation targets for treating depression. BEHAVIOURAL BRAIN RESEARCH. Amsterdam: Elsevier Science, 2019, roč. 359, Feb 2019, s. 266-273. ISSN 0166-4328. Dostupné z: https://dx.doi.org/10.1016/j.bbr.2018.11.004. URL info
• DAMBORSKÁ, Alena, Miralena, I. TOMESCU, Eliška HONZÍRKOVÁ, Elis BARTEČKŮ, Jana HOŘÍNKOVÁ, Sylvie FEDOROVÁ, Šimon ONDRUŠ a Christoph M. MICHEL. EEG Resting-State Large-Scale Brain Network Dynamics Are Related to Depressive Symptoms. Frontiers in Psychiatry. Lausanne: Frontiers, 2019, roč. 10, č. 548, s. 1-10. ISSN 1664-0640. Dostupné z: https://dx.doi.org/10.3389/fpsyt.2019.00548. URL info
• DAMBORSKÁ, Alena, Camille PIGUET, Jean-Michel AUBRY, Alexandre G. DAYER, Christoph M. MICHEL a Cristina BERCHIO. Altered Electroencephalographic Resting-State Large-Scale Brain Network Dynamics in Euthymic Bipolar Disorder Patients. Frontiers in Psychiatry. Lausanne: Frontiers, 2019, roč. 10, NOV 15 2019, s. 1-10. ISSN 1664-0640. Dostupné z: https://dx.doi.org/10.3389/fpsyt.2019.00826. URL info
• KUKLETA, Miloslav, Alena DAMBORSKÁ, Baris TURAK a Jacques LOUVEL. Evoked potentials in final epoch of self-initiated hand movement: A study in patients with depth electrodes. International Journal of Psychophysiology. AMSTERDAM: Elsevier Science, 2017, roč. 117, July, s. 119-125. ISSN 0167-8760. Dostupné z: https://dx.doi.org/10.1016/j.ijpsycho.2017.05.004. info
• DAMBORSKÁ, Alena, Robert ROMAN, Milan BRÁZDIL, Ivan REKTOR a Miloslav KUKLETA. Post-movement processing in visual oddball task - Evidence from intracerebral recording. Clinical Neurophysiology. Clare: Elsevier Ireland, 2016, roč. 127, č. 2, s. 1297-1306. ISSN 1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2015.08.014. URL info
• KUKLETA, Miloslav, Alena DAMBORSKÁ, Robert ROMAN, Ivan REKTOR a Milan BRÁZDIL. The primary motor cortex is involved in the control of a non-motor cognitive action. Clinical Neurophysiology. Clare: Elsevier Ireland, 2016, roč. 127, č. 2, s. 1547-1550. ISSN 1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2015.11.049. URL info
• ROMAN, Robert, Milan BRÁZDIL, Jan CHLÁDEK, Ivan REKTOR, Pavel JURÁK, Miroslav SVĚTLÁK, Alena DAMBORSKÁ, Daniel Joel SHAW a Miloslav KUKLETA. Hippocampal negative event-related potential recorded in humans during a simple sensorimotor task occurs independently of motor execution. Hippocampus. Hoboken, USA: WILEY-BLACKWELL, 2013, roč. 23, č. 12, s. 1337-1344. ISSN 1050-9631. Dostupné z: https://dx.doi.org/10.1002/hipo.22173. URL info
• SVĚTLÁK, Miroslav, Petr BOB, Robert ROMAN, Stanislav JEŽEK, Alena DAMBORSKÁ, Jan CHLÁDEK, Daniel Joel SHAW a Miloslav KUKLETA. Stress-Induced Alterations of Left-Right Electrodermal Activity Coupling Indexed by Pointwise Transinformation. Physiological Research. Prague: Academy of Sciences of the Czech Republic, Institute of Physiology, 2013, roč. 62, č. 6, s. 711-719. ISSN 0862-8408. URL info
• DAMBORSKÁ, Alena, Milan BRÁZDIL, Ivan REKTOR, Eva JANOUŠOVÁ, Jan CHLÁDEK a Miloslav KUKLETA. Late divergence of target and nontarget ERPs in a visual oddball task. Physiological Research. Praha: Akademie věd ČR, 2012, roč. 61, č. 3, s. 307-318. ISSN 0862-8408. info

2022/01/14