Assoc. Prof. RNDr. Petr Matula, Ph.D.

Department head – Department of Computer Graphics and Design

Office: A310
Botanická 554/68a
602 00 Brno

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Phone: +420 549 49 4973

Curriculum vitae

Person Identification
  • Petr Matula, Ph.D., married, 1 child
  • Faculty of Informatics
    Masaryk University
    Botanicka 68a
    602 00 Brno
    Czech Republic
Employment Position
  • Researcher and lecturer
Education and Academic Qualifications
  • 2013: Associate Professor of Computer Science, Faculty of Informatics, Masaryk University, Brno. Habilitation thesis: "Automated Image Analysis in Fluorescence Microscopy"
  • 2003: PhD in Computer Science, Faculty of Informatics, Masaryk University (FI MU), PhD Thesis: "Image registration and its applications in fluorescence microsopy"
  • 1998 - 2002: doctoral studies at FI MU
  • 1998: MSc in Computer Science, FI MU, Master Thesis: "Recognition of Czech hand-written text" (in Czech)
  • 1993 - 1998: master studies at FI MU
  • 1989 - 1993: a secondary school specialized in mathematics
Employment overview
  • 2005 - present: researcher and lecturer at FI MU
  • 2011-2012: 1.5 year, researcher, Center for Mathematical Morphology, MINES ParisTECH, Fontainebleau, France
  • 2007-2008: 1.5 year, postdoc, Biomedical Computer Vision Group, German Cancer Research Center (DKFZ) Heidelberg and University of Heidelberg
  • 2003 - 2005: researcher at FI MU
Pedagogical Activities
  • 2014-present: Introduction to Digital Image Processing
  • 2008-present: Mathematical Morphology
  • 2004-present: Biomedical Image Processing Project
  • 2001-present: Advisor of numerous bachelor and master theses
  • 2007-2015: Seminar on Digital Image Processing
  • 2002-2012: Labs on Digital Image Processing
  • 2005-2007: Advanced Methods of Digital Image Processing
  • 1996-1997: Seminar on Design of Algorithms
Scientific and Research Activities
  • 2015-2017: Development of new MUS81 nuclease inhibitors as chemical biology probe with clinical progression, Grant Agency of Masaryk University, MUNI/M/1894/2014, co-investigator
  • 2014-2016: Development and Study of Methods for Live Cell Quantification, Czech grant agency, GA14-22461S, principal investigator 2013-2015: High-throughput screening of compound libraries aimed on discovery of novel inhibitors of the FGFR/ERK MAP kinase signaling, Grant Agency of Masaryk University, MUNI/M/0071/2013, co-investigator
  • 2012-2018: Dynamics and Organization of Chromosomes in the Cell Cycle and during Di fferentiation under Normal and Pathological Conditions, team member
  • 2012-2015: Development of human resources in the field of cell biology, CELLBIOL, OPVK, scientific manager
  • 2011-2012 Image analysis of multi-photon microscopy images of human skin, L'Oreal Research, France, team member
  • 2011-2012 Image analysis of reflectance confocal microscopy images of human skin, L'Oreal Research, France, team member
  • 2007-2011 VIROQUANT: Systems biology of virus-cell interactions, German FORSYS initiative, Bundesministerium fuer Bildung und Forschung (BMBF), Germany, team member
  • 2006-2011 Marker selection, screening and early diagnostics of cancer diseases using highly automated multidimensional biomedical image processing. Ministry of Education, Czech Republic, Project No. 2B06052, team member
  • 2005-2011 Highly parallel and distributed computing systems, Ministry of Education, Czech Republic, Project No. MSM-0021622419, team member
Academical Stays
  • 2010: one month, Center for Mathematical Morphology, Fontainebleau, France
  • 2005: one month, Quantitative Imaging Group, Technical University of Delft, the Netherlands
University Activities
  • 2013-present Head of Department of Computer Graphics and Design
Membership in Scientific Societes
  • 2002-present: Member of Czechoslovak Microscopy Society (CSMS)
  • 2002-present: Member of European Microscopy Society (EMS)
  • 2004-present: Member of Czech Society for Analytical Cytology (CSAC)
  • 2004-2007: Member of IEEE Society
Prizes and Awards
  • 2003: The Masaryk University Rector's Prize (awarded anually to the best PhD students)
Selected Publications
  • HÖLSCHER, Christina, Florian SONNTAG, Katharina HENRICH, Qingxin CHEN, Jürgen BENEKE, Petr MATULA, Karl ROHR, Lars KADERALI, Nina BEIL, Holger ERFLE, Jürgen A KLEINSCHMIDT a Müller MARTIN. The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses. PLoS Pathogens, Public Library of Science, 2015, roč. 11, č. 12, s. e1005281. ISSN 1553-7366. doi:10.1371/journal.ppat.1005281. info
  • MAŠKA, Martin, Vladimír ULMAN, David SVOBODA, Pavel MATULA, Petr MATULA, Cristina EDERRA, Ainhoa URBIOLA, Tomás ESPAÑA, Subramanian VENKATESAN, Deepak M W BALAK, Pavel KARAS, Tereza BOLCKOVÁ, Markéta ŠTREITOVÁ, Craig CARTHEL, Stefano CORALUPPI, Nathalie HARDER, Karl ROHR, Klas E G MAGNUSSON, Joakim JALDÉN, Helen M BLAU, Oleh DZYUBACHYK, Pavel KŘÍŽEK, Guy M HAGEN, David PASTOR-ESCUREDO, Daniel JIMENEZ-CARRETERO, Maria J LEDESMA-CARBAYO, Arrate MUÑOZ-BARRUTIA, Erik MEIJERING, Michal KOZUBEK a Carlos ORTIZ-DE-SOLORZANO. A Benchmark for Comparison of Cell Tracking Algorithms. Bioinformatics, 2014, roč. 30, č. 11, s. 1609-1617. ISSN 1367-4803. doi:10.1093/bioinformatics/btu080. URL info
  • LISAUSKAS, Tautvydas, Petr MATULA, Christoph CLAAS, Susanne REUSING, Stefan WIEMANN, Holger ERFLE, Lars LEHMANN, Peter FISCHER, Roland EILS, Karl ROHR, Brian STORRIE a Vytaute STARKUVIENE. Live cell assays to identify regulators of ER to Golgi trafficking. Traffic, John Wiley & Sons, 2012, roč. 13, č. 3, s. 416–432. ISSN 1398-9219. doi:10.1111/j.1600-0854.2011.01318.x. info
  • SERVA, Andrius, Bettina KNAPP, Yueh-Tso TSAI, Christoph CLASS, Tautvydas LISAUSKAS, Petr MATULA, Nathalie HARDER, Lars KADERALI, Karl ROHR, Holger ERFLE, Roland EILS, Vania BRAGA a Vytaute STARKUVIENE. miR-17-5p Regulates Endocytic Trafficking through Targeting TBC1D2/Armus. PLoS One, 2012, roč. 7, č. 12, s. e52555. ISSN 1932-6203. doi:10.1371/journal.pone.0052555. info
  • REISS, S., Ilka REBHAN, P. BACKES, I. ROMERO-BREY, Holger ERFLE, Petr MATULA, Lars KADERALI, Marion POENISCH, H. BLANKENBURG, M.S. HIET, T. LONGERICH, S. DIEHL, F. RAMIREZ, T. BALLA, Karl ROHR, A. KAUL, S. BÜHLER, Rainer PEPPERKOK, T. LENGAUER, M. ALBRECHT, Roland EILS, P. SCHIRMACHER, V. LOHMANN a Ralf BARTENSCHLAGER. Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host & Microbe, 2011, roč. 9, č. 1, s. 32-45. ISSN 1931-3128. doi:10.1016/j.chom.2010.12.002. info
  • STAIER, Florian, Heinz EIPEL, Petr MATULA, Alexei V EVSIKOV, Michal KOZUBEK, Christoph CREMER a Michael HAUSMANN. Micro axial tomography: A miniaturized, versatile stage device to overcome resolution anisotropy in fluorescence light microscopy. Rev. Sci. Instrum., USA: American Institute of Physica, 2011, roč. 82, č. 9, s. "093701-1"-"093701-8". ISSN 0034-6748. info
  • MATULA, Petr, Tautvydas LISAUSKAS, Vytaute STARKUVIENE a Karl ROHR. Quantification of Golgi Complex Assembly and Disassembly in LiveCell Fluorescence Microscopy Images. In Proceedings of Workshop on Microscopic Image Analysis with Applications in Biology. Neuveden: Neuveden, 2011. 4 s. URL info
  • KNAPP, Bettina, Ilka REBHAN, Anil KUMAR, Petr MATULA, Narsis A KIANI, Marco BINDER, Hoger ERFLE, Karl ROHR, Roland EILS, Ralf BARTENSCHLAGER a Lars KADERALI. Normalizing for Individual Cell Population Context in the Analysis of High-Content Cellular Screens. BMC Bioinformatics, BioMed Central, 2011, roč. 12, č. 485, s. 1-14. ISSN 1471-2105. URL info
  • MATULA, Petr, Fatima VERISSIMO, Stefan WÖRZ, Roland EILS, Rainer PEPPERKOK a Karl ROHR. Quantification of Fluorescent Spots in Time Series of 3D Confocal Microscopy Images of Endoplasmic Reticulum Exit Sites Based on the HMAX Transform. In Proceedings of SPIE Medical Imaging. Neuveden: Neuveden, 2010. 7 s. ISBN 978-0-8194-8027-9. URL info
  • SURATANEE, Apichat, Ilka REBHAN, Petr MATULA, Anil KUMAR, Lars KADERALI, Karl ROHR, Ralf BARTENSCHLAGER, Roland EILS a Rainer KÖNIG. Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images. Bioinformatics, 2010, roč. 26, č. 18, s. i653-i658. ISSN 1367-4803. info
  • MATULA, Petr, Anil KUMAR, Ilka WÖRZ, Holger ERFLE, Ralf BARTENSCHLAGER, Roland EILS a Karl ROHR. Single-cell-based image analysis of high-throughput cell array screens for quantification of viral infection. Cytometry Part A, UNITED STATES: John Wiley & Sons, Inc., 2009, roč. 75A, č. 4, s. 309-318. ISSN 1552-4922. URL info
  • MATULA, Pavel, Martin MAŠKA, Ondřej DANĚK, Petr MATULA a Michal KOZUBEK. Acquiarium: Free Software for the Acquisition and Analysis of 3D Images of Cells in Fluorescence Microscopy. In IEEE International Symposium on Biomedical Imaging. Boston: IEEE, 2009. s. 1138-1141, 4 s. ISBN 978-1-4244-3932-4. URL info
  • MATULA, Petr, Anil KUMAR, Ilka WÖRZ, Nathalie HARDER, Holger ERFLE, Ralf BARTENSCHLAGER, Roland EILS a Karl ROHR. Automated analysis of siRNA screens of cells infected by hepatitis C and dengue viruses based on immunofluorescence microscopy images. In Proceedings of SPIE. 6916. vyd. 2008. ISSN 0277-786X. URL info
  • MATULA, Petr, Pavel MATULA, Michal KOZUBEK a Vladimír DVOŘÁK. Fast Point-Based 3D Alignment of Live Cells. IEEE Transactions on Image Processing, 2006, roč. 15, č. 8, s. 2388-2396. ISSN 1057-7149. info
  • MATULA, Pavel, Petr MATULA, Michal KOZUBEK a Petr MEJZLÍK. High-Resolution Cytometry Network Project: Client/Server System for 3D Optical Microscope Data Storage and Analysis. In 2nd International Symposium on 3D Data Processing, Visualization, and Transmission. Los Alamitos: IEEE Computer Society, 2004. s. 580-583, 4 s. ISBN 0-7695-2223-8. info
  • KOZUBEK, Michal, Petr MATULA, Pavel MATULA a Stanislav KOZUBEK. Automated acquisition and processing of multidimensional image data in confocal in vivo microscopy. Microscopy research and technique, USA: Wiley-Liss, 2004, roč. 64, č. 2, s. 164-175. ISSN 1059-910X. info
  • MATULA, Petr, Michal KOZUBEK, Florian STAIER a Michael HAUSMANN. Precise 3D image alignment in micro-axial tomography. Journal of Microscopy, Oxford: Blackwell Science, 2003, roč. 209, č. 2, s. 126-142. ISSN 0022-2720. info
  • KOZUBEK, Michal, Magdalena SKALNÍKOVÁ, Petr MATULA, Eva BÁRTOVÁ, Joachim RAUCH, Friedrich NEUHAUS, Heinz EIPEL a Michael HAUSMANN. Automated micro axial tomography of cell nuclei after specific labelling by fluorescence in situ hybridisation. Micron, Amsterdam: Elsevier, 2002, roč. 33, č. 7, s. 655-665. ISSN 0968-4328. info
  • KOZUBEK, Michal, Petr MATULA, Heinz EIPEL a Michael HAUSMANN. Automated multi-view 3D image acquisition in human genome research. In 3D data processing, visualization and transmission. Los Alamitos: IEEE Computer Society, 2002. s. 91-98. ISBN 0-7695-1521-5. info
  • KOZUBEK, Michal a Petr MATULA. An efficient algorithm for measurement and correction of chromatic aberrations in fluorescence microscopy. Journal of Microscopy, Oxford: Blackwell Science, 2000, roč. 200, č. 3, s. 206-217. ISSN 0022-2720. abstract info


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