prof. RNDr. Viktor Brabec, DrSc.
Total number of publications: 78
2005
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Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked by trans-diamminedichloroplatinum(II)
BIOPOLYMERS, year: 2005, volume: 77, edition: 4
2004
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DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.
Biochemical Pharmacology, year: 2004, volume: 67, edition: 6
2003
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Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action
Journal of Biological Chemistry, year: 2003, volume: 278, edition: 48
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DNA Binding Mode of the Cis and Trans Geometries of New Antitumor Nonclassical Platinum Complexes Containing Piperidine, Piperazine, or 4-Picoline Ligand in Cell-Free Media. Relations to Their Activity in Cancer Cell Lines
Biochemistry, year: 2003, volume: 42, edition: 20
2002
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A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464
Journal of Biological Inorganic Chemistry, year: 2002, volume: 2002, edition: 7
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Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium
Journal of Biological Inorganic Chemistry, year: 2002, volume: 7, edition: 7
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DNA modifications by antitumor platinum and ruthenium compounds: their recognition and repair
Progress in Nucleic Acid Research and Molecular Biology, year: 2002, number of pages: 68 s.
2001
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Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464
Journal of Biological Chemistry, year: 2001, volume: 276, edition: 25
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Different recognition of DNA modified by antitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53
Journal of Biological Chemistry, year: 2001, volume: 276, edition: 19
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Study of the Interactions of Anticancer Metal-Based Drugs with DNA.
9th ECSBM, Book of Abstracts, year: 2001