Publication details
Pityriasis rubra pilaris - popis případu
| Title in English | Pityriasis rubra pilaris - a case study |
|---|---|
| Authors | |
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Česká dermatovenerologie |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | pityriasis rubra pilaris; erythroderma; palmoplantar keratoderma; follicular hyperkeratosis; retinoids |
| Description | Pityriasis rubra pilaris is a rare chronic papulosquamous skin disorder of unknown aetiology. It is characterized by reddish orange scaly plaques, palmoplantar keratoderma, and keratotic follicular papules. The disease may progress and develop into erythroderma with patches of unaffected skin. Pityriasis rubra pilaris is divided into 6 types. With type I, the skin tends to heal within 3 years in 80% patients. The diagnosis is usually made on the basis of a correlation of clinical and histological findings. No single therapeutic modality is fully effective; retinoids, PUVA and methotrexate and recently also TNF-alfa inhibitors are the preparations most commonly used for treatment. This case study presents the case of 43-year-old man, with papulosquamous exanthema, progressing during two months to erythroderma. The skin began to recede after a 2-week therapy of acitretin. The long-lasting course of the disease has had a strong negative impact on the patient’s psychological life. |