Publication details

Detekce sarkosinu v moči pacientů s karcinomem prostaty

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Title in English Detection of sarcosine in ithe urine of prostate cancer patients

CERNEI Natalia Vladimirovna SOCHOR Jiří ZÍTKA Ondřej KŘÍŽKOVÁ Soňa GUMULEC Jaromír MASAŘÍK Michal ECKSCHLAGER Tomáš ADAM Vojtěch KIZEK René

Year of publication 2012
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Description This study provides important new information about MT expression at the protein level in prostate cancer cells. The results of immunohistochemical and electrochemical analyzes that MT expression in malignant prostate cells down regulated compared to normal prostatic cell line. We attribute this effect rapidly reduced concentration of zinc ions, which is a normal situation in the prostate is relatively high. The exact explanation for this phenomenon is not yet known (Costello et al.). Therefore, in further experimental work we focus only on the MT but also the zinc transporters that this process plays an important role.
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