Publication details
Germinom thalamu u dítěte s projevy předčasné pseudopuberty - kazuistika
| Title in English | Thalamic germinoma in a child with symptoms of precocious pseudopuberty - A case report |
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| Authors | |
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Česká a Slovenská neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.lexum.cz/o-ocni-klinice-lexum/news/oftalmologove-z-jiznich-cech-na-seminari-kliniky-lexum |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | Central nervous system; Chemotherapy; Germinoma; Human chorionic gonadotropin; Pseudopuberty; Radiotherapy |
| Description | We describe a case of a 6 years old boy with germinoma of an unusual thalamic localization that presented with precocious pseudopuberty based on ectopic human chorionic gonadotropin (hCG) secretion. The tumour was confirmed with stereotactic biopsy; subsequent chemotherapy and radiotherapy led to complete remission. The mechanism of precocious pseudopuberty and clinical and treatment aspects of brain germinomas in children are discussed. |