Publication details

The Molecular Typing Data of Recently Identified Subtype 11q/j of Treponema pallidum subsp. pallidum Suggest Imported Case of Yaws.

Title in English The molecular typing data of recently identified subtype 11q/j of treponema pallidum subsp. pallidum suggest imported case of yaws
Authors

MIKALOVÁ Lenka STROUHAL Michal GRILLOVÁ Linda ŠMAJS David

Year of publication 2014
Type Article in Periodical
Magazine / Source Sexually transmitted diseases
MU Faculty or unit

Faculty of Medicine

Citation
Field Epidemiology, infectious diseases and clinical immunology
Keywords WHOLE GENOME SEQUENCE; STRAINS; SYPHILIS; PERTENUE; GENE; CONSERVATION; DIFFER
Description In the article ‘‘Molecular Subtyping of Treponema pallidum in Paris, France,’’ published in Sexually Transmitted Diseases journal (Vol. 40, No. 8, August 2013), Grange et al.1 identified 3 subtypes that are sporadically present in the human population, that is, subtypes 11q/j, 14d/d, and 15d/f. Interestingly, subtype 11q/j showed a unique typing pattern ‘‘q’’ corresponding to a new restriction profile after MseI digestion of the tprE,G,J genes (Centers for Disease Control and Prevention [CDC] typing system)2 and ‘‘j’’ corresponding to a new sequence type within the 83-basepair region of the tp0548 gene (enhanced CDC typing system).3 This genital specimen was isolated from an HIV-negative MSM (men who have sex with men) patient with diagnosed primary syphilis.
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