Publication details

Prenatally detected rare case of the fetal facial rhabdomyosarcoma



Year of publication 2014
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

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Description Rhabdomyosarcoma is a mesenchymal highly malignant neoplasm. RMS is the most common soft tissues tumor of childhood,but its prenatal occurence is very rare, but also can have a genetic underlay associated with some rare familial “cancer syndromes”.We present a case of 27-year old primigravida with the singleton pregnancy. She was referred to our department at 30 weeks of gestation with the suspected facial tumor. Anomaly scan at the first and second trimester were both normal. Ultrasound showed mostly solid mass 77x52 mm with the small cystic portion arising from the right orbit and dislocating the bulb. The third part of the tumor expanding intracranially. Doppler flow in the mass was present. MRI confirm our finding, amniocentesis showed normal karyotype 46 XX. Differential diagnosis we consider teratoma or rhabdomyosarcoma. Due to the rapid growth of the tumor, its inauspicious location and 31+5 gestational age parents decided to the late termination of the pregnancy. The fetocide was done and at the same day we vaginally delivered baby girl 2370g and 46cm without no maternal injury. Postnatal autopsy confirmed rhabdomyosarcoma. We would like to point out that the fetal occurrence of head-and-neck RMS is very rare but possible. The prognosis of RMS tumor finally depends on staging and histological subtype. We consider the prognosis of our fetus in such circumstances highly adverse.

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