Publication details

A Bambusuril Macrocycle that Binds Anions in Water with High Affinity and Selectivity

Authors

YAWER Mirza Arfan HAVEL Václav ŠINDELÁŘ Vladimír

Year of publication 2015
Type Article in Periodical
Magazine / Source Angewandte Chemie International Edition
MU Faculty or unit

Faculty of Science

Citation
Web http://onlinelibrary.wiley.com/doi/10.1002/anie.201409895/abstract;jsessionid=ABCDEB2B3122226D3B80E184E66BCDB5.f02t03
Doi http://dx.doi.org/10.1002/anie.201409895
Field Organic chemistry
Keywords anion recognition; host–guest systems; macrocycles; self-assembly; supramolecular chemistry
Description Synthetic receptors that function in water are important for the qualitative and quantitative detection of anions, which may act as pollutants in the environment or play important roles in biological processes. Neutral receptors are particularly appealing because they are often more selective than positively charged receptors; however, their affinity towards anions in pure water is only in range of 1-10(3)Lmol(-1). The anion-templated synthesis of a water-soluble bambusuril derivative is shown to be an outstanding receptor for various inorganic anions in pure water, with association constants of up to 10(7)Lmol(-1). Furthermore, the macrocycle discriminates between anions with unprecedented selectivity (up to 500000-fold). We anticipate that the combination of remarkable affinity and selectivity of this macrocycle will enable the efficient detection and isolation of diverse anions in aqueous solutions, which is not possible with current supramolecular systems.
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