Publication details

Česká multicentrická výzkumná databáze těžké chronické obstrukční plicní nemoci - popis projektu

Title in English	Czech multicentric research database of severe chronic obstructive pulmonary disease - project description
Authors	KOBLÍŽEK Vladimír NOVOTNÁ Barbora KOČOVÁ Eva POPELKOVÁ Patrice PLUTINSKÝ Marek ZATLOUKAL Jaromír DVOŘÁK Tomáš SOBOTÍK Ondřej ŠAFRÁNEK Petr ŠNELEROVÁ Blanka HERIBANOVÁ Lucie MUSILOVÁ Pavlína MAJERČIAKOVÁ Marie VENCÁLEK Tomáš HEJDUK Karel PRAUS Rudolf VYTŘÍSALOVÁ Magda HRONEK Miloslav KOVAŘÍK Miroslav NEUMANNOVÁ Kateřina KOPECKÝ Michal ZBOŽÍNKOVÁ Zuzana JARKOVSKÝ Jiří ŠVANCARA Jan PAVLÍKOVÁ Ladislava KONEČNÝ Tomáš ORBAN Marek VANÍK Petr LIPTÁKOVÁ Zuzana MAREL Miloslav VLACHOVÁ Alena BLAŽKOVÁ Šárka KUDELA Ondřej PEJCHAL Jiří JAŠKOVÁ Jana VOLÁKOVÁ Eva BRAT Kristián JAREŠOVÁ Šárka KRIEGOVÁ Eva KOLEK Vítězslav DUŠEK Ladislav
Year of publication	2015
Type	Article in Periodical
Magazine / Source	Postgraduální medicína
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pneumology
Keywords	COPD; phenotypes; comorbidities; exacerbations; mortality; prospective study
Description	Introduction: Chronic obstructive pulmonary disease (COPD) is a frequently occurring condition with many clinical forms. COPD represents a significant factor causing increased morbidity and mortality especially among the elderly. Coals: The primary goal of the project is to record and analyse the course of the disease and its impact of the overall patient mortality in relation to the GOLD categories and COPD phe-notypes. Other goals include: monitoring respiratory and cardiovascular morbidity, evaluating decline in pulmonary function, monitoring bodily composition, describing adherence to using inhalation drugs, periodically examining daily activities analysing comorbidities, Methods: The Czech multicentric research database of COPD is planned for the period of 7-8 years (2-3 years of patient targeting and enrolment followed by 5 years of systematic monitoring). The project is observatory and prospective, taking place in 13 hospital centres in the Czech Republic. The main indication criterion is presence of COPD with a severe bronchial construction and post-bronchodilation value of FEV1<60 %. Both patients satisfying the indication criteria and not satisfying exclusion criteria are to be included. Being included in the project will not affect the patients' treatment in any way. Summary: The subject of this article is an exhaustive description of the goals and methods of this project. Initial entry data has already been analysed and published. First results of prospective monitoring will be available during 2016. The project enables us to better describe the appearance and natural course of COPD in patients with severe bronchial obstruction treated in the Czech Republic.