Publication details
Pokračovací udržovací léčba pemetrexedemu u nemocných s nemalobuněčným karcinomem plic v České republice
| Title in English | Continuation maintenance therapy with pemetrexed in patients with non-small-cell lung cancer in the Czech Republic |
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| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Pneumology |
| Keywords | non-small-cell lung cancer; chemotherapy; continuation maintenance therapy; pemetrexed |
| Description | Lung carcinoma is among the leading cancers by incidence and mortality both worldwide and in the Czech Republic. In the recent years, there has been considerable progress in NSCLC treatment. Already at the time of diagnosis, efforts are made to establish the morphological diagnosis as precisely as possible and, when indicated, to perform genetic testing. This particularly applies to non-squamous NSCLC. In 2013, the efficacy and safety data of continuation maintenance monotherapy with pemetrexed were reported and, owing to the positive outcome, this treatment has been available in the Czech Republic since May 2013. Our páper presents a group of 134 evaluated patients who received the above-mentioned treatment. In reál clinical practice in the Czech Republic, continuation maintenance therapy with pemetrexed achieved better results than the registration study, and the treatment was tolerated very well. So far, the medián overall survival (OS) has been determined to be 23.5 months. |