Evolution of COPD phenotypes in time - Czech multicentre research database of severe COPD

• Authors: KOBLIZEK Vladimir; NOVOTNA Barbora; ŠVANCARA Jan; SVOBODA Michal; POPELKOVA Patrice; PLUTINSKÝ Marek; BRAT Kristián; ZATLOUKAL Jaromir; VOLAKOVA Eva; HEJDUK Karel; KOCOVA Eva; KOPECKY Michal; NEUMANNOVA Katerina; FECANINOVA Miroslava; SAFRANEK Petr; DVORAK Tomas; SOBOTIK Ondrej; LIPTAKOVA Zuzana; HERIBANOVA Lucie; SNELEROVA Blanka; MAJERCIAKOVA Marie; MUSILOVA Pavlina; JARKOVSKÝ Jiří
• Year of publication: 2016
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: COPD is a condition with several clinical variants:non-exacerbation phenotype(NON-AE),frequent exacerbations with chronic bronchitis(AE CB),frequent exacerbations without chronic bronchitis(AE NON-CB),and asthma-COPD overlap syndrome(ACOS).The evolution of COPD phenotypes in time and their impact on lung function and symptoms remains largely unknown. Methods: The Czech Research Database of COPD(NCT01923051)is a multicentre,observational,and prospective study of consecutive patients with severe COPD.Signs identifying phenotypes, lung function, and respiratory symptoms were assessed annually.