Publication details

Syndrom mnohočetné chemické přecitlivělosti

Title in English Multiple chemical sensitivity

HRUBÁ Drahoslava PEŘINA Aleš

Year of publication 2017
Type Article in Periodical
Magazine / Source Praktický lékař
MU Faculty or unit

Faculty of Medicine

Field Public health care, social medicine
Keywords multiple chemical sensitivity; low-levels exposure; mechanisms; treatment
Description The term multiple chemical sensitivity (MCS) has been adopted for the description of individual's multiorgan sensitivities following exposures to very low levels of chemicals commonly tolerated by majority of people. People with MCS obviously response to odours by acute respiratory distress, palpitations, skin eruptions and other physical symptoms. The spectrum of chemical triggers becomes wider over time; the reactions become more severe and long lasting. A large number of lexicological, immunological, psychological and neurological mechanisms have been suggested, but none of them could clearly explain the basis of MCS. It is also discussed a possibility of some genetic predisposition. It is estimated that about 9-33% of the population can show the MCS responses, about 2% of them ask physicians for the help. MCS can seriously disrupt the quality of life. Unfortunately, this uncertainty about aetiology and pathogenesis of MCS is attended with the absence of effective treatment. The clinical approach advices to adopt chemical-free, isolated lifestyle, which can minimize continual exposure. The neuro-behavioural approach is oriented on the stress coping, even with the support of antidepressive drugs. The recent recommendation is the multidisciplinary approach (general practitioners, immunologists, allergists, gynaecologists, dentists, neurologists, psychologists) after controlling and excluding of possible somatic or psychiatric disease.

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