Publication details

Optimization of media cultivation for intestinal sulfate-reducing bacteria



Year of publication 2017
Type Conference abstract
MU Faculty or unit

Faculty of Science

Description Intestinal sulfate-reducing bacteria (SRB) are anaerobic microorganisms which make part of animal and human large intestine microbiota. Hydrogen sulfide is a final product of SRB metabolism. Its production in the high concentration has negative impact on epithelial cells of the large bowel. This toxic compound can be involved in intestinal inflammation and affects gastrointestinal motility, secretion and nociception, and leads to diseases like an ulcerative colitis, Crohn's disease or even cancer. Isolation of SRB from the mixture of human and animals’ microbiota and their cultivation is also difficult. Some species of SRB such as Bilophila wadsworthia and Lawsoni intracellularis are uncultured. Other genera of the Desulfovibrionaceae family also grow poorly in cultivation medium or are uncultured.
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