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Stanovení vývojového potenciálu lidských embryí pomocí omických disciplín

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Title in English 'Omics' techniques: Genomics, Transcriptomics, Proteomics and Metabolomics in Embryo Developmental Capacity Assessment

MÁDR Aleš GLATZ Zdeněk CRHA Igor

Year of publication 2017
Type Article in Periodical
Magazine / Source Chemické listy
MU Faculty or unit

Faculty of Science

Field Biochemistry
Keywords assisted reproduction; human embryo; in vitro fertilization; genomics; transcriptomics; proteomics; metabolomics;
Description This review defines limits of currently used techniques to assess developmental capacity of human embryos in assisted reproduction and provides an overview of techniques assessing embryo’s physiology on levels of genomics, transcriptomics, proteomics and metabolomics. Basic principles of respective techniques are covered and discovered biomarkers are discussed with respect to biochemical functions and its prognostic value of embryonal development.
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