Publication details

Radial artery neointimal hyperplasia after transradial PCI-Serial optical coherence tomography volumetric study

Authors

KALA Petr KAŇOVSKÝ Jan NOVÁKOVÁ Tereza MIKLÍK Roman BOČEK Otakar POLOCZEK Martin JEŘÁBEK Petr PRÝMKOVÁ Lenka ONDRÚŠ Tomáš JARKOVSKÝ Jiří BLAHA Milan MINTZ G.S.

Type Article in Periodical
Magazine / Source Plos one
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1371/journal.pone.0185404
Field Cardiovascular diseases incl. cardiosurgery
Keywords Transradial catheterization
Description Aims Transradial catheterization (TRC) is a dominant access site for coronary catheterization and percutaneous coronary interventions (PCI) in many centers. Previous studies reported higher intimal thickness of the radial artery (RA) wall in patients with a previous history of TRC. In this investigation the aim was to assess the intimal changes of RA using the optical coherence tomography (OCT) intravascular imaging in a serial manner. Methods and results 100 patients with the diagnosis of non-ST-elevation myocardial infarction (nSTEMI) treated by PCI were enrolled (6 patients were excluded from this analysis because of occluded RA at follow-up [2 patients] and insufficient quality of OCT images [4 patients]). An 54mm long OCT run of the RA was performed immediately after the index PCI and repeated 9 months later. Volumetric analyses of the intimal layer and lumen changes were conducted. Median intimal volume at baseline versus 9 months was 33.9mm(3) (19.0; 69.4) versus 39.0mm(3) (21.7; 72.6) (p<0.001); and median arterial lumen volume was 356.3mm(3) (227.8; 645.3) versus 304.7mm(3) (186.1; 582.7) (p<0.001). There was no significant difference in the effect of any clinical factor on the RA volume changes. Conclusions OCT volumetric analyses at baseline and 9 months showed a significant increase in the radial artery intimal layer volume and a decrease in lumen volume after transradial PCI. No significant factors affecting this process were identified.