Publication details
Možnosti léčby hidradenitis suppurativa
| Title in English | Treatment of hidradenitis suppurativa |
|---|---|
| Authors | |
| Year of publication | 2017 |
| Type | Article in Periodical |
| Magazine / Source | Dermatologie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | hidradenitis suppurativa; treatment; adalimumab |
| Description | Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory disease characterized by deep painful nodules, abscesses, sinus tracts and scarring. The most common areas affected are the axillae, the groin, the buttocks, the anogenital and perineal region, inframammary areas. Its pathogenesis is multifactorial and includes genetic aspects, immune dysregulation, smoking and obesity. The treatment of HS depends on the severity of the disease (according to Hurley classification) and on its activity (according to Physician's Global Assessment). First-line treatment includes topical clindamycin, oral doxycyclin or oral clindamycin and adalimumab. Surgical treatment includes deroofing, incision of inflammatory lesions, reconstruction with flap piasty, carbon dioxide laser therapy, Nd:YAG laser, total excision of the lesions and surrounding hair-bearing skin and second intention healing. |