Publication details

Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis

Authors

JANČAŘÍKOVÁ Gita HOUSER Josef DOBEŠ Pavel HYRŠL Pavel WIMMEROVÁ Michaela

Year of publication 2017
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Science

Citation
Description Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity.
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