Publication details

Human cardiac progenitor analysis in dystrophin cardiomyopathy after cardiac transplantation

Authors

PEŠL Martin JELÍNKOVÁ Šárka CALUORI Guido HOLICKÁ Mária ŽAMPACHOVÁ Víta NĚMEC Petr DVOŘÁK Petr ROTREKL Vladimír

Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description We report for the first time human dystrophy (Becker type, BMD) cardiac progenitor analysis. Following rare cardiac transplantation in case of a symptomatic BMD samples were obtained and compared to healthy control samples. Heart failure is a frequent cause of death in muscle dystrophy patients. We hypothesized lower repair capacity of myocardium, possibly due to decreased percentage of reparative c-kit+ cells and their impaired migration capacity.
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