Publication details
Ochranné faktory kognitivního deficitu u roztroušené sklerózy
| Title in English | Protective factors for cognitive impairment in multiple sclerosis |
|---|---|
| Authors | |
| Year of publication | 2018 |
| Type | Article in Periodical |
| Magazine / Source | Česká a slovenská neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.14735/amcsnn201824 |
| Keywords | multiple sclerosis;cognition;cognitive reserve;neuropsychology |
| Description | Multiple sclerosis is often accompanied by cognitive deficits that occur in all stages and subtypes of the disease. Given the significantly negative impact of cognitive impairment on the over all quality of life of patients, we need to ask which factors help maintain cognitive function. The cur rent review addresses the protective role of the brain reserve and, in particular, the cognitive reserve built by lifetime intellectual enrichment. We summarize recent findings based on these factors, such as verbal intelligence, education, occupation attainment or participation in cognitively stimulating leisure activities that may contribute to a better neuropsychological prognosis. The studies show that not only hereditary factors and premorbid behavior but even ongoing participation in cognitively stimulating activities may attenuate the negative effects of the disease on cognitive status. Limitations of the cur rent research and its future directions are discussed. |